Renin gene polymorphism: its relationship to hypertension, renin levels and vascular responses

B Sun, JS Williams, L Pojoga… - Journal of the Renin …, 2011 - journals.sagepub.com
… arterial pressure (MAP), plasma renin activity (PRA) and the … Our results confirm that
polymorphisms in the renin gene are … renin activity and vascular responsiveness to angiotensin II. …

Comprehensive analysis of the renin–angiotensin gene polymorphisms with relation to hypertension in the Japanese

N Kato, T Sugiyama, H Morita, H Kurihara… - Journal of …, 2000 - journals.lww.com
… No significant association was observed between the individual R–A gene polymorphisms
and hypertension status in our case–control study. The results were almost unchanged when …

Significance of genetic polymorphisms of the renin–angiotensin–aldosterone system in cardiovascular and renal disease

M Rudnicki, G Mayer - Pharmacogenomics, 2009 - Taylor & Francis
… AT1R genetic polymorphisms alone or in combination with the ACE I/D polymorphism influence
… Furthermore, it is not clear how these polymorphisms affect response to ACE inhibitor or …

A biallelic gene polymorphism of CYP11B2 predicts increased aldosterone to renin ratio in selected hypertensive patients

J Nicod, D Bruhin, L Auer, B Vogt… - The Journal of …, 2003 - academic.oup.com
… in renin and … low renin levels, with a higher proportion of low renin in blacks than in whites
(2). Moreover, up to 15% of unselected hypertensives have a raised aldosterone to renin ratio (…

Aspects of gene polymorphisms in cardiovascular disease: the renin‐angiotensin system

M Carluccio, M Soccio… - European journal of …, 2001 - Wiley Online Library
… Thus, the first association reported between a genetic polymorphism and the occurrence of
… A strong association between the gene polymorphism and ACE activity was confirmed, while …

Renin–angiotensin system gene polymorphisms: potential mechanisms for their association with cardiovascular diseases

AHJ Danser, H Schunkert - European journal of pharmacology, 2000 - Elsevier
… reported associations between this polymorphism and cardiovascular diseases… renin–angiotensin
system gene polymorphisms, most notably the angiotensinogen M235T polymorphism

Gene polymorphisms of the renin-angiotensin system and early development of hypertension

M Barbalić, T karić-Jurić, F Cambien… - American journal of …, 2006 - academic.oup.com
… In conclusion, the present study detected the association of ACE gene polymorphisms with
premature hypertension, whereas no association with AGT and AT1R gene polymorphisms

Genetic polymorphisms in the renin–angiotensin system: relevance for susceptibility to cardiovascular disease

JG Wang, JA Staessen - European journal of pharmacology, 2000 - Elsevier
… /I polymorphism of the angiotensin-converting enzyme gene possibly also with coronary heart
disease. Several other gene polymorphisms… area of the angiotensinogen gene, have been …

Genetic Polymorphism of CYP11B2 Gene and Hypertension in Japanese

S Tamaki, N Iwai, Y Tsujita, M Kinoshita - Hypertension, 1999 - Am Heart Assoc
gene may be a genetic marker for low-renin hypertension in Japanese. Low-renin hypertension
is characterized by high ratio … of CYP11B2 gene polymorphisms to hypertension, while …

[HTML][HTML] Genetic polymorphisms of the renin-angiotensin-aldosterone system in end-stage renal disease

E Lovati, A Richard, BM Frey, FJ Frey, P Ferrari - Kidney international, 2001 - Elsevier
… We have analyzed three gene polymorphisms of the RAS for association with ESRD. The
RAS is a logical target because (1) an increased activity of the RAS causes angiotensin II-…