Renin gene polymorphism: its relationship to hypertension, renin levels and vascular responses
B Sun, JS Williams, L Pojoga… - Journal of the Renin …, 2011 - journals.sagepub.com
… arterial pressure (MAP), plasma renin activity (PRA) and the … Our results confirm that
polymorphisms in the renin gene are … renin activity and vascular responsiveness to angiotensin II. …
polymorphisms in the renin gene are … renin activity and vascular responsiveness to angiotensin II. …
Comprehensive analysis of the renin–angiotensin gene polymorphisms with relation to hypertension in the Japanese
N Kato, T Sugiyama, H Morita, H Kurihara… - Journal of …, 2000 - journals.lww.com
… No significant association was observed between the individual R–A gene polymorphisms
and hypertension status in our case–control study. The results were almost unchanged when …
and hypertension status in our case–control study. The results were almost unchanged when …
Significance of genetic polymorphisms of the renin–angiotensin–aldosterone system in cardiovascular and renal disease
M Rudnicki, G Mayer - Pharmacogenomics, 2009 - Taylor & Francis
… AT1R genetic polymorphisms alone or in combination with the ACE I/D polymorphism influence
… Furthermore, it is not clear how these polymorphisms affect response to ACE inhibitor or …
… Furthermore, it is not clear how these polymorphisms affect response to ACE inhibitor or …
A biallelic gene polymorphism of CYP11B2 predicts increased aldosterone to renin ratio in selected hypertensive patients
J Nicod, D Bruhin, L Auer, B Vogt… - The Journal of …, 2003 - academic.oup.com
… in renin and … low renin levels, with a higher proportion of low renin in blacks than in whites
(2). Moreover, up to 15% of unselected hypertensives have a raised aldosterone to renin ratio (…
(2). Moreover, up to 15% of unselected hypertensives have a raised aldosterone to renin ratio (…
Aspects of gene polymorphisms in cardiovascular disease: the renin‐angiotensin system
M Carluccio, M Soccio… - European journal of …, 2001 - Wiley Online Library
… Thus, the first association reported between a genetic polymorphism and the occurrence of
… A strong association between the gene polymorphism and ACE activity was confirmed, while …
… A strong association between the gene polymorphism and ACE activity was confirmed, while …
Renin–angiotensin system gene polymorphisms: potential mechanisms for their association with cardiovascular diseases
AHJ Danser, H Schunkert - European journal of pharmacology, 2000 - Elsevier
… reported associations between this polymorphism and cardiovascular diseases… renin–angiotensin
system gene polymorphisms, most notably the angiotensinogen M235T polymorphism …
system gene polymorphisms, most notably the angiotensinogen M235T polymorphism …
Gene polymorphisms of the renin-angiotensin system and early development of hypertension
… In conclusion, the present study detected the association of ACE gene polymorphisms with
premature hypertension, whereas no association with AGT and AT1R gene polymorphisms …
premature hypertension, whereas no association with AGT and AT1R gene polymorphisms …
Genetic polymorphisms in the renin–angiotensin system: relevance for susceptibility to cardiovascular disease
JG Wang, JA Staessen - European journal of pharmacology, 2000 - Elsevier
… /I polymorphism of the angiotensin-converting enzyme gene possibly also with coronary heart
disease. Several other gene polymorphisms… area of the angiotensinogen gene, have been …
disease. Several other gene polymorphisms… area of the angiotensinogen gene, have been …
Genetic Polymorphism of CYP11B2 Gene and Hypertension in Japanese
S Tamaki, N Iwai, Y Tsujita, M Kinoshita - Hypertension, 1999 - Am Heart Assoc
… gene may be a genetic marker for low-renin hypertension in Japanese. Low-renin hypertension
is characterized by high ratio … of CYP11B2 gene polymorphisms to hypertension, while …
is characterized by high ratio … of CYP11B2 gene polymorphisms to hypertension, while …
[HTML][HTML] Genetic polymorphisms of the renin-angiotensin-aldosterone system in end-stage renal disease
E Lovati, A Richard, BM Frey, FJ Frey, P Ferrari - Kidney international, 2001 - Elsevier
… We have analyzed three gene polymorphisms of the RAS for association with ESRD. The
RAS is a logical target because (1) an increased activity of the RAS causes angiotensin II-…
RAS is a logical target because (1) an increased activity of the RAS causes angiotensin II-…
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