Ischemia-reperfusion injury leads to distinct temporal cardiac remodeling in normal versus diabetic mice

M Eguchi, YH Kim, KW Kang, CY Shim, Y Jang… - PloS one, 2012 - journals.plos.org
… of diabetes on cardiac dysfunction and remodeling after ischemia reperfusion (IR) injury in
mice… artery for 30 min followed by reperfusion for up to 42 days. We first evaluated changes in …

Impact of lymphangiogenesis on cardiac remodeling after ischemia and reperfusion injury

Y Shimizu, R Polavarapu, KL Eskla… - Journal of the …, 2018 - Am Heart Assoc
… Postischemic cardiac remodeling and dysfunction are closely linked to inflammation. We, …
treatment on cardiac remodeling and dysfunction. Analysis at 28 days of reperfusion revealed …

The role of oxidative stress in myocardial ischemia and reperfusion injury and remodeling: revisited

GA Kurian, R Rajagopal, S Vedantham… - … medicine and cellular …, 2016 - Wiley Online Library
… purported to reverse the cardiac remodeling might serve as tenable … /reperfusion injury
[117]. The central role of ROS in the pathogenesis of DCM and ischemia/reperfusion injury is …

Multilineage contribution of CD34+ cells in cardiac remodeling after ischemia/reperfusion injury

J Xie, L Jiang, J Wang, Y Yin, R Wang, L Du… - Basic Research in …, 2023 - Springer
… ventricular fibrosis after ischemia/reperfusion (I/R) injury with improved cardiac function. This
study … as crucial contributors to cardiac remodeling and function after the I/R injury, with their …

Local delivery of a senolytic drug in ischemia and reperfusion-injured heart attenuates cardiac remodeling and restores impaired cardiac function

JR Lee, BW Park, JH Park, S Lim, SP Kwon, JW Hwang… - Acta biomaterialia, 2021 - Elsevier
… Myocardial ischemia-reperfusion (IR) generates stress-induced senescent cells (SISCs)
that play an important role in the pathophysiology of adverse cardiac remodeling and heart …

Targeting chronic cardiac remodeling with cardiac progenitor cells in a murine model of ischemia/reperfusion injury

JC Deddens, DA Feyen, PP Zwetsloot, MA Brans… - PLoS …, 2017 - journals.plos.org
… I/R injury in NOD-SCID mice does not result in sufficient cardiac damage [28], we show
successful induction of cardiac remodeling upon I/R injury. … target chronic cardiac remodeling. In …

The Nrf-2/ARE–HO-1 axis: An important therapeutic approach for attenuating myocardial ischemia and reperfusion injury-induced cardiac remodeling

J Wang, X Hu, H Jiang - International …, 2015 - internationaljournalofcardiology.com
… myocardial ischemia/reperfusion (I/R) injury involves in a complex pathophysiological process
which can further induce cardiac remodeling [2]. Cardiac remodeling leads to progressive …

Pharmacological modulation of cardiac remodeling after myocardial infarction

W Zhao, J Zhao, J Rong - Oxidative Medicine and Cellular …, 2020 - Wiley Online Library
… ), and transforming growth factor β-induced gene-h3 (TGFBI) in the border zone at 15
days after reperfusion in a porcine model of ischemia/reperfusion injury [79]. Collectively, the …

Proteomics analysis of cardiac extracellular matrix remodeling in a porcine model of ischemia/reperfusion injury

J Barallobre-Barreiro, A Didangelos, FA Schoendube… - Circulation, 2012 - Am Heart Assoc
… late-stage ECM remodeling after myocardial ischemia/reperfusion injury, which may have
… Novel proteins in cardiac remodeling after ischemia/reperfusion (I/R) injury are highlighted …

Dual inhibition of cathepsin G and chymase reduces myocyte death and improves cardiac remodeling after myocardial ischemia reperfusion injury

B Hooshdaran, MA Kolpakov, X Guo, SA Miller… - Basic research in …, 2017 - Springer
… and differentiation that play a role in adverse cardiac remodeling and function post-IR. Thus,
… novel therapeutic strategy to reduce post-IR inflammation and improve cardiac remodeling. …