The sequence of the repetitive motif influences the frequency of multistep mutations in Short Tandem Repeats

S Antão-Sousa, N Pinto, P Rende, A Amorim… - Scientific Reports, 2023 - nature.com
… with repetitive motif CTTTT (25% of the detected mutations) and the lowest frequency
corresponding to the group with repetitive motifs … between groups with repetitive motifs with …

Sequencing and characterizing short tandem repeats in the human genome

HA Tanudisastro, IW Deveson, H Dashnow… - Nature Reviews …, 2024 - nature.com
Short tandem repeats (STRs) are highly polymorphic repetitive sequences of short (1–6 bp)
motifs … STR variability can refer to changes in repeat length, motif structure and sequence. …

[PDF][PDF] DNA recommendations: Further report of the DNA Commission of the ISFH regarding the use of short tandem repeat systems*

W Bär, B Brinkmann, B Budowle… - International Journal of …, 1997 - academia.edu
… It is sometimes possible to define different repetitive motifs, even though the choice of the
strand is clear. In the two following examples, the initial point for reading the repeat motif is …

Screening of repetitive motifs inside the genome of the flat oyster (Ostrea edulis): transposable elements and short tandem repeats

M Vera, X Bello, JA Álvarez-Dios, BG Pardo, L Sánchez… - Marine genomics, 2015 - Elsevier
… Here, new generation genomic resources were used to analyse the repetitive fraction of the
short tandem repeats identified in WG were tetranucleotide motifs while trinucleotide motifs

Evolutionary footprints of short tandem repeats in avian promoters

H Abe, NJ Gemmell - Scientific reports, 2016 - nature.com
… The simplest explanation is that several nucleotide substitutions in repetitive motifs would
precede the slippage dinucleotide mutation particularly between recently diverged groups. …

A genomic view of short tandem repeats

M Gymrek - Current opinion in genetics & development, 2017 - Elsevier
Short tandem repeats (STRs), also known as microsatellites, consist of repeating motifs of
1–6 base pairs (bp) and comprise about 3% of the human genome [1]. Their repetitive nature …

The motif composition of variable number tandem repeats impacts gene expression

TY Lu, PN Smaruj, G Fudenberg, N Mancuso… - Genome …, 2023 - genome.cshlp.org
… Variable number tandem repeats (VNTRs) are repetitive DNA sequences with the size of
a repeat unit >6 nucleotides. The copy number of a repeat unit is hypervariable owing to its …

Sequence composition changes in short tandem repeats: heterogeneity, detection, mechanisms and clinical implications

IS Rajan-Babu, E Dolzhenko, MA Eberle… - Nature Reviews …, 2024 - nature.com
Short tandem repeats (STRs) are a class of repetitive elements composed of tandem arrays
of 1–6 base pair sequence motifs 1 … as its genomic context and sequence motif (Table 1). For …

The effects of transcription and recombination on mutational dynamics of short tandem repeats

M Zavodna, A Bagshaw, R Brauning… - Nucleic acids …, 2018 - academic.oup.com
Short tandem repeats (STRs), or microsatellites, are DNA sequences, typically less than
100-bp long, in which motifs of 1–6 bp are repeated in tandem. They are abundantly distributed …

Patterns of tandem repetition in plant whole genome assemblies

R Navajas-Pérez, AH Paterson - Molecular Genetics and Genomics, 2009 - Springer
tandem repeats composed of shorter monomeric units (especially dinucleotide and 9–30-bp
repeats), while higher repetitive … As for the telomeric sequences, we have found the motif (…