… RNA replication foci. We find that, of the three transmembrane proteins, the membrane protein
… compartment before the spike and envelope proteins. Relocation of a lysosome marker …

… , together with membranes derived from host organelles, compose the virion envelope, the
N protein binds the gRNA and allows its encapsulation into viral particles (13). Virions are …

… vesicles with an outer layer containing N protein and a hollow center (Figure 3B, left image).
We propose that these N protein layers are formed at the viral replication organelles (vRO). …

… To investigate this possibility, we used antibodies against several of the structural proteins,
namely, the nucleocapsid protein N, the envelope membrane protein M, and the spike protein …

… all viral replication centers with liquid‐like properties are entirely consistent with the LLPS
model, 78 so the precise nature of these membraneless organelles requires additional study. …

… aspects of protein and RNA condensation Several membrane-bound organelles exist in the
… the key biological functions that occur in membraneless organelles (MLOs) implicated in a …

… -16 and N protein establish a viral replication-transcriptional complex (RTC) and reshape
the cell … to form replicating organelles, which are essential for keeping RNA replicated and …

… nucleocapsid of 25 to 35 nm composed of the 12.7 to 15.7 kb RNA genome and the nucleocapsid
protein … recruitment of this organelle to supply the energy needed for replication and/or …

Coronavirus genome replication is associated with virus-induced cytosolic double-… messenger
RNAs can travel from these sealed replication compartments to the cytosol to ensure their …

… LLPS gives rise to actual membraneless organelles (MLOs), … SARS-CoV-2 nucleocapsid
protein to favor the packaging of … -2 replication by recruiting the excess of cytoplasmic proteins …