Requirement for glucose in ligand-stimulated meiotic maturation of cumulus cell-enclosed mouse oocytes

CF Fagbohun, SM Downs - Reproduction, 1992 - rep.bioscientifica.com
… that the energy substrate requirements for spontaneous … mouse oocytes cultured in vitro.
In addition, removal of the cumulus cells results in dramatic changes in the response of oocytes

The influence of glucose, cumulus cells, and metabolic coupling on ATP levels and meiotic control in the isolated mouse oocyte

SM Downs - Developmental biology, 1995 - Elsevier
… cumulus cell-enclosed oocytes after 18 hr in glucose-free but not glucose-supplemented
medium. Thus, cumulus cells were required to achieve a decrease in oocyte ATP levels as well …

Metabolism of radiolabeled glucose by mouse oocytes and oocyte-cumulus cell complexes

SM Downs, AM Utecht - Biology of reproduction, 1999 - academic.oup.com
… (PRPP), a compound required for the purine de … glucose metabolism in cumulus-oocyte
complexes during hormone-stimulated maturation using [1- 14 C]-, [6- 14 C]-, and [5- 3 H]glucose

Glucose requirement for mouse sperm capacitation in vitro

PC Hoppe - Biology of Reproduction, 1976 - academic.oup.com
Requirements for the three energy substrates (glucose, lactate and pyruvate) which are present
in Whitten’s medium for fertilization of mouse ova in … Thus, glucose is the major source of …

[PDF][PDF] The pivotal role of glucose metabolism in determining oocyte developmental competence

ML Sutton-McDowall, RB Gilchrist, JG Thompson - Reproduction, 2010 - researchgate.net
… Ali AA, Bilodeau JF & Sirard MA 2003 Antioxidant requirements for bovine oocytes varies …
developmental competence by mouse oocytes in vitro: FSH, insulin, glucose and ascorbic acid. …

Glucose utilization during gonadotropin‐induced meiotic maturation in cumulus cell‐enclosed mouse oocytes

SM Downs, PG Humpherson… - Molecular …, 1996 - Wiley Online Library
… The first series of experiments, involving lactate assays and assessment of GVB to determine
the temporal glucose requirement and possible role of glycolysis in FSH-induced meiotic …

Altered meiotic regulation in oocytes from diabetic mice

SA Colton, GM Pieper, SM Downs - Biology of reproduction, 2002 - academic.oup.com
mouse oocytes have indicated that glucose is required for … glucose during bovine oocyte
maturation has been demonstrated, but exposure of maturing oocytes to high levels of glucose

Effects of glucose metabolism during in vitro maturation on cytoplasmic maturation of mouse oocytes

HL Xie, YB Wang, GZ Jiao, DL Kong, Q Li, H Li… - Scientific reports, 2016 - nature.com
… that the glucose requirement for meiotic induction does not depend on its glycolysis to
pyruvate 29,30,31,32,33,34 . Based on their finding that purine nucleotide-generating pathways …

Effect of varying glucose and glucosamine concentration in vitro on mouse oocyte maturation and developmental competence

LA Frank, ML Sutton-McDowall… - Reproduction …, 2013 - CSIRO Publishing
… of glucose on the COC affect oocyte competence during spontaneous in vitro maturation. In
particular, there is a requirement for glucose to … Further studies are required to establish the …

Conditions that affect acquisition of developmental competence by mouse oocytes in vitro: FSH, insulin, glucose and ascorbic acid

JJ Eppig, M Hosoe, MJ O'Brien, FM Pendola… - Molecular and cellular …, 2000 - Elsevier
… The simplest unit required for the support of oocyte growth and development is the … our
culture system for mouse oocyte development in vitro, by changing the glucose concentration, by …