Minimal residual disease in leukaemia patients

T Szczepariski, A Orfão, VHJ van der Valden… - The lancet …, 2001 - thelancet.com
… Standardized RT-PCR analysis of fusion gene transcripts from chromosome aberrations in
acute leukemia for detection of minimal residual disease. Report of the BIOMED-1 Concerted …

[HTML][HTML] Molecular minimal residual disease in acute myeloid leukemia

M Jongen-Lavrencic, T Grob… - … England Journal of …, 2018 - Mass Medical Soc
Patients with acute myeloid leukemia (AML) often reach complete remission, but relapse …
the detection of molecular minimal residual disease in virtually every patient, but its clinical …

Minimal residual disease in acute lymphoblastic leukemia

D Campana - Seminars in hematology, 2009 - Elsevier
… In patients with acute lymphoblastic leukemia (ALL), monitoring of minimal residual disease
… ALL is well demonstrated; studies in adult patients also support its prognostic value. Hence, …

Prognostic and therapeutic implications of minimal residual disease detection in acute myeloid leukemia

F Buccisano, L Maurillo, MI Del Principe… - Blood, The Journal …, 2012 - ashpublications.org
… In this view, measure of minimal residual disease (MRD) promises to be an efficient tool to
establish on an individual basis the patient's leukemia's susceptibility to treatment, enhancing …

Clinical significance of minimal residual disease in leukemia.

S Faderl, HM Kantarjian… - … journal of oncology, 2000 - spandidos-publications.com
patients, relapse is thought to result from subclinical levels of residual leukemia, termed
minimal residual disease (… a patient with a high level of residual disease detected by PCR (>102 …

Why and how to quantify minimal residual disease in acute lymphoblastic leukemia?

T Szczepański - Leukemia, 2007 - nature.com
… Evaluation of candidate control genes for diagnosis and residual disease detection in
leukemic patients using ‘real-time’ quantitative reverse-transcriptase polymerase chain reaction (…

Monitoring of minimal residual disease in acute myeloid leukemia

W Kern, C Haferlach, T Haferlach… - … International Journal of …, 2008 - Wiley Online Library
… Treatment of patients with acute myeloid leukemia (AML) … strong correlations of minimal
residual disease (MRD) … evaluation by MFC at diagnosis to identify leukemia-associated aberrant …

Measurement of residual disease in acute myeloid leukemia

RS Vedula, RC Lindsley - Current Hematologic Malignancy Reports, 2017 - Springer
… Assessment of measurable residual disease (MRD) after treatment can identify patients with
acute myeloid leukemia (AML) that are at high risk of poor outcomes. However, there is no …

Minimal residual disease in acute myeloid leukemia: coming of age

E Paietta - Hematology 2010, the American Society of …, 2012 - ashpublications.org
… assay's ability to classify patients as high MRD (ie, when the number of leukemic blasts in a
… accuracy in defining patients with low MRD (ie, when the number of leukemic cells in a tissue …

Immunophenotyping investigation of minimal residual disease is a useful approach for predicting relapse in acute myeloid leukemia patients

JF San Miguel, A Martınez, A Macedo… - Blood, The Journal …, 1997 - ashpublications.org
… Furthermore, we have explored whether residual disease was … Patients with ≥5 × 10 −3
residual leukemic cells at the end … those with less than 5 × 10 −3 residual cells (mean, 32% ± 31…