… detecting residual disease are based on biologic properties that allow acute leukemia
cells … Techniques used to detect residual disease in acute leukemia include the reverse …

… of the daily risk of relapse in patients with residual disease to the risk in patients without …
Our results differ from those of studies showing that leukemic cells persist in most patients during …

… residual leukemic cells in ALL patients. The advent of novel techniques, namely next
generation flow cytometry (NGF), digital-droplet-PCR (ddPCR), and next generation sequencing (…

… has significantly increased and minimal residual disease (MRD) levels … patient outcome,
as reported in the first study of our Group for Research on Adult Acute Lymphoblastic Leukemia …

… Study Group for Adult Acute Lymphoblastic Leukemia. Clinical significance of minimal residual
disease quantification in adult patients with standard-risk acute lymphoblastic leukemia.  …

… of minimal residual disease quantification in adult patients with … of minimal residual
disease in childhood acute lymphoblastic leukemia: … Leukemia. 2004;18(10):1630-1636.PubMed…

… CBF leukemia patients destined to relapse from those who can be cured with chemotherapy
alone. Clinically relevant threshold transcript levels were defined, with studies consistently …

… patients, the measurement of residual leukemia levels, “minimal … residual disease in
childhood acute lymphoblastic leukemia. … of Cancer–Childhood Leukemia Cooperative Group. …

… (which may include allogeneic stem cell transplantation) and to create risk profiles for
patients based on measured clearance of leukemic cells and post-treatment probability of …

… failure for patients with acute lymphoblastic leukemia (… leukemic cells in a proportion of
samples with no morphologic evidence of leukemia, a finding termed “minimal residual disease (…