Eliminating minimal residual disease as a therapeutic end point: working toward cure for patients with CLL
PA Thompson, WG Wierda - … Journal of the American Society of …, 2016 - ashpublications.org
… , so-called minimal residual disease (MRD). These residual cells ultimately are responsible
… on the quantity of residual disease and kinetics of residual leukemia cell division. Sensitive …
… on the quantity of residual disease and kinetics of residual leukemia cell division. Sensitive …
Assessment of minimal residual disease in standard-risk AML
A Ivey, RK Hills, MA Simpson… - … England Journal of …, 2016 - Mass Medical Soc
… defined with the use of leukemia-specific molecular markers (… levels of leukemia, so-called
minimal residual disease, after … Patients with minimal residual disease in peripheral blood …
minimal residual disease, after … Patients with minimal residual disease in peripheral blood …
Chronic lymphocytic leukemia therapy guided by measurable residual disease
T Munir, DA Cairns, A Bloor, D Allsup… - … England Journal of …, 2024 - Mass Medical Soc
… We previously assessed ibrutinib plus venetoclax in patients with relapsed–refractory CLL,
with the duration of therapy defined by the time to undetectable measurable residual disease (…
with the duration of therapy defined by the time to undetectable measurable residual disease (…
[HTML][HTML] Measurable residual disease in acute lymphoblastic leukemia: methods and clinical context in adult patients
… as a method of measurable residual disease detection in acute lymphoblastic leukemia. An
… patient with B-cell acute lymphoblastic leukemia (B-ALL). The measurable residual disease (…
… patient with B-cell acute lymphoblastic leukemia (B-ALL). The measurable residual disease (…
Acute lymphoblastic leukemia: monitoring minimal residual disease as a therapeutic principle
M Brüggemann, N Gökbuget, M Kneba - Seminars in oncology, 2012 - Elsevier
… cytometric techniques for the quantitative detection of residual leukemic cells, the presence
of minimal residual disease (MRD) in patients in complete clinical remission has clearly been …
of minimal residual disease (MRD) in patients in complete clinical remission has clearly been …
Minimal residual disease studies in acute leukemia
D Campana - Pathology Patterns Reviews, 2004 - academic.oup.com
… by morphologic examination was 30.0% ± 17.7% for patients who had residual disease of
0.1% or more in the postinduction 1 sample and 72.1% ± 11.5% for those who had fewer or no …
0.1% or more in the postinduction 1 sample and 72.1% ± 11.5% for those who had fewer or no …
Measurable residual disease as a biomarker in acute myeloid leukemia: theoretical and practical considerations
… ”) residual disease (MRD) in acute myeloid leukemia (AML). Although the perfect MRD test
does not (yet) exist, the strong association between MRD and adverse patient outcomes has …
does not (yet) exist, the strong association between MRD and adverse patient outcomes has …
High stem cell frequency in acute myeloid leukemia at diagnosis predicts high minimal residual disease and poor survival
A Van Rhenen, N Feller, A Kelder, AH Westra… - Clinical cancer …, 2005 - AACR
… In most cases, patients can be treated effectively with chemotherapy … leukemic cells, called
minimal residual disease (MRD; refs. 2–5). MRD can be detected in the majority of patients in (…
minimal residual disease (MRD; refs. 2–5). MRD can be detected in the majority of patients in (…
WT1 as a new prognostic factor and a new marker for the detection of minimal residual disease in acute leukemia
K Inoue, H Sugiyama, H Ogawa, M Nakagawa… - 1994 - ashpublications.org
… minimal residual disease (MRD) in acute leukemia regardless … mRNA was performed for 9
patients with acute leukemia. In 4 … from leukemia patients at the onset of their disease before …
patients with acute leukemia. In 4 … from leukemia patients at the onset of their disease before …
Minimal residual disease in acute myeloid leukaemia
CS Hourigan, JE Karp - Nature reviews Clinical oncology, 2013 - nature.com
… Minimal residual disease measurement during or … patients to identify those most likely to
benefit from escalated or additional therapy For patients in complete remission minimal disease …
benefit from escalated or additional therapy For patients in complete remission minimal disease …