Current approaches for assessing insulin sensitivity and resistance in vivo: advantages, limitations, and appropriate usage

R Muniyappa, S Lee, H Chen… - American Journal of …, 2008 - journals.physiology.org
… that appropriately predicts changes in insulin sensitivity after therapeutic interventions as …
use of current in vivo measures of insulin sensitivity/resistance. insulin is an essential peptide …

Measurement of Insulin Resistance In Vivo

S Del Prato - Drugs, 1999 - Springer
… into quartiles showed that those falling in the lowest quartile had insulin sensitivities as low
as those observed in the most insulin resistant of patients with type 2 diabetes. Low insulin

Assessment of Insulin Sensitivity in Vivo

RN Bergman, DT Finegood, M Ader - Endocrine reviews, 1985 - academic.oup.com
… Under conditions of extreme insulin resistance, or substantial insulin sensitivity, SSPG
may enter a range where its value is significantly influenced by physiologic factors other than …

[HTML][HTML] Analysis of in vitro insulin-resistance models and their physiological relevance to in vivo diet-induced adipose insulin resistance

KA Lo, A Labadorf, NJ Kennedy, MS Han, YS Yap… - Cell reports, 2013 - cell.com
… The in vivo and in vitro insulin-resistance models demonstrate a striking expression
pattern that is the opposite of that induced by adipogenesis (Figure 2A): many adipogenesis-induced …

How to measure insulin sensitivity

E Ferrannini, A Mari - Journal of hypertension, 1998 - journals.lww.com
… The importance of the insulin-resistant phenotype for the … for measuring insulin resistance
in vivo. The euglycaemic … to evaluate insulin sensitivity in vivo [ 27 ] was the insulin-tolerance …

[HTML][HTML] Acute in vivo effects of insulin on gene expression in adipose tissue in insulin-resistant and insulin-sensitive subjects

J Westerbacka, A Corner, K Kannisto, M Kolak… - Diabetologia, 2006 - Springer
… genes adversely affecting insulin sensitivity hyperrespond to insulin, while genes enhancing
insulin sensitivity hyporespond to insulin in insulin-resistant human adipose tissue in vivo. …

Insulin resistance in the aged: a quantitative evaluation of in vivo insulin sensitivity and in vitro glucose transport

G Pagano, M Cassader, P Cavallo-Perin, A Bruno… - Metabolism, 1984 - Elsevier
… should shift the insulin sensitivity curve to the right, both in vivo (euglycemic … RESISTANCE
has been demonstrated in aged subjects, for whom a reduction in fat cell receptors for insulin

[HTML][HTML] Apple polyphenol extract improves insulin sensitivity in vitro and in vivo in animal models of insulin resistance

M Manzano, MD Giron, JD Vilchez, N Sevillano… - Nutrition & …, 2016 - Springer
… In vivo study showed that nutritional intervention with APE induced an increase of insulin
sensitivity with an increase of glucose infusion rate (GIR) of 45 %. Additionally, in vitro results …

The dual function of hepatic SOCS3 in insulin resistance in vivo

T Torisu, N Sato, D Yoshiga, T Kobayashi… - Genes to …, 2007 - Wiley Online Library
… cKO) mice and examined insulin sensitivity. Being consistent with a … insulin sensitivity.
However, unexpectedly, L-SOCS3 cKO mice exhibited obesity and systemic insulin resistance with …

Relationship between in vivo insulin resistance and decreased insulin receptors in obese man

OG KOLTERMAN, GM REAVEN… - The Journal of Clinical …, 1979 - academic.oup.com
vivo insulin sensitivity and decreased adipocyte insulin receptors; 2) the in vivo dose-response
relationship between plasma insulin … that decreased target tissue insulin receptors are the …