Resistance to polymyxins: mechanisms, frequency and treatment options

ME Falagas, PI Rafailidis, DK Matthaiou - Drug resistance updates, 2010 - Elsevier
Resistance to polymyxins is generally less than 10%. In specific … be useful options for the
treatment of polymyxin-resistant gram-… A summary of the resistance mechanisms is presented in …

Insight into Acinetobacter baumannii: pathogenesis, global resistance, mechanisms of resistance, treatment options, and alternative modalities

M Asif, IA Alvi, SU Rehman - Infection and drug resistance, 2018 - Taylor & Francis
… we discuss its taxonomy, pathogenesis, current treatment options, global resistance rates,
mechanisms of its resistance against various groups of antimicrobials, and future therapeutics. …

Mechanisms of osimertinib resistance and emerging treatment options

S Schmid, JJN Li, NB Leighl - Lung Cancer, 2020 - Elsevier
resistance. This review will summarize mechanisms of resistance overall and in different
treatment settings and will focus on potential new treatment options targeting specific acquired …

Drug resistance in epilepsy: clinical impact, potential mechanisms, and new innovative treatment options

W Löscher, H Potschka, SM Sisodiya, A Vezzani - Pharmacological reviews, 2020 - ASPET
… therapies that may overcome drug resistance. Here, we will … , and structural mechanisms
of ASD resistance and discuss … mechanisms underpinning epilepsies and drug resistance by …

[HTML][HTML] An overview of the antimicrobial resistance mechanisms of bacteria

WC Reygaert - AIMS microbiology, 2018 - ncbi.nlm.nih.gov
… These bacterial weapons pretty much cover all of the antimicrobial agents that we have,
and there are probably more resistance mechanisms out there that we have not yet …

Resistance to BRAF inhibitors: unraveling mechanisms and future treatment options

J Villanueva, A Vultur, M Herlyn - Cancer research, 2011 - AACR
… We have many options and agents available for combination treatments, and increasing
knowledge about the molecular mechanisms that underlie drug resistance will facilitate the …

Steroid resistance in asthma: mechanisms and treatment options

IM Adcock, PA Ford, P Bhavsar, T Ahmad… - Current allergy and …, 2008 - Springer
… with corticosteroid-resistant asthma. Understanding the molecular mechanisms of GR action
and … asthma pathogenesis and new treatment options that have been obtained as a result. …

ALK‐positive non–small cell lung cancer: Mechanisms of resistance and emerging treatment options

CE Steuer, SS Ramalingam - Cancer, 2014 - Wiley Online Library
Treatment with crizotinib demonstrated that the TKI-resistant cells were able to … treatment
with an EGFR inhibitor in addition to ALK inhibition to subvert this resistance mechanism and, if …

Epidermal growth factor receptor–mutant lung cancer: new drugs, new resistance mechanisms, and future treatment options

Z Piotrowska, LV Sequist - The Cancer Journal, 2015 - journals.lww.com
… lung cancers with acquired resistance mechanisms to erlotinib and … of resistance mechanisms
has grown, post-resistance therapy is increasingly tailored based on the type of resistance

[HTML][HTML] Emerging treatment options for multi-drug-resistant bacterial infections

R Giurazza, MC Mazza, R Andini, P Sansone, MC Pace… - Life, 2021 - mdpi.com
… , including those available for the treatment of AMR pathogens. In this article, … -resistant
bacteria and their main resistance mechanisms, we describe the emerging antimicrobial options