Multidrug-resistant Klebsiella pneumoniae: mechanisms of resistance including updated data for novel β-lactam-β-lactamase inhibitor combinations

I Galani, I Karaiskos, H Giamarellou - Expert Review of Anti …, 2021 - Taylor & Francis
… Introduction: Multi-drug-resistant Klebsiella pneumoniae is currently one of the most
pressing emerging issues in bacterial resistance. Treatment of K.pneumoniae infections is often …

Emergence of Oxacillinase-Mediated Resistance to Imipenem in Klebsiella pneumoniae

L Poirel, C Héritier, V Tolün… - Antimicrobial agents and …, 2004 - Am Soc Microbiol
Klebsiella pneumoniae strain 11978 was isolated in Turkey in 2001 and was found to be …
the β-lactamase content of a K. pneumoniae isolate that was resistant to all available β-…

[HTML][HTML] High rates of metallo-beta-lactamase-producing Klebsiella pneumoniae in Greece-a review of the current evidence

A Vatopoulos - Eurosurveillance, 2008 - eurosurveillance.org
… -resistant, VIM-1-producing Klebsiella pneumoniae. The proportion of imipenem-resistant K.
… problem, the GSSAR data reveal a steep increase in the proportion of imipenem-resistant K. …

[HTML][HTML] Worldwide diversity of Klebsiella pneumoniae that produce β-lactamase blaKPC-2 gene

G Cuzon, T Naas, HV Truong, MV Villegas… - Emerging infectious …, 2010 - ncbi.nlm.nih.gov
Resistance of Klebsiella pneumoniae to carbapenems is mainly … carbapenem-hydrolyzing
β-lactamases (1). These β-… clinical Klebsiella pneumoniae isolates that produce β-lactamase

Detection of extended-spectrum beta-lactamases in clinical isolates of Klebsiella pneumoniae and Escherichia coli

GA Jacoby, P Han - Journal of clinical microbiology, 1996 - Am Soc Microbiol
… coli and 141 isolates of Klebsiella pneumoniae that either transferred ceftazidime resistance
or showed sulbactam enhancement of oxyimino- -lactam susceptibility were tested by disk …

Roles of β-Lactamases and Porins in Activities of Carbapenems and Cephalosporins against Klebsiella pneumoniae

L Martínez-Martínez, A Pascual… - Antimicrobial agents …, 1999 - Am Soc Microbiol
… extended-spectrum β-lactamase (ESBL)-producing Klebsiella pneumoniae were noted to be
… The role of β-lactamase in resistance was investigated by eliminating the original ESBL and …

… pneumoniae resistant to broad-spectrum cephalosporins and beta-lactam-beta-lactamase inhibitor combinations by hyperproduction of SHV-5 beta-lactamase

GL French, KP Shannon… - Journal of Clinical …, 1996 - Am Soc Microbiol
… a hospital outbreak of aminoglycoside-resistant K. pneumoniae resistant to broad-spectrum
cephalosporins and to amoxicillin-clavulanic acid and other available β-lactam–β-lactamase …

The changing face of Klebsiella pneumoniae infections in the community

Y Keynan, E Rubinstein - International journal of antimicrobial agents, 2007 - Elsevier
Klebsiella pneumoniae (Kp) is an important pathogen both in the community and the …
frequency of resistance to β-lactam antibiotics, a change in the class of β-lactamases has also been …

Extended-Spectrum β-Lactamase-Producing Escherichia coli and Klebsiella pneumoniae: Risk Factors for Infection and Impact of Resistance on Outcomes

E Lautenbach, JB Patel, WB Bilker… - Clinical infectious …, 2001 - academic.oup.com
… β-lactamase (… resistant to β-lactam agents has increased sharply in recent years. At 144
hospitals in the United States, the prevalence of ceftazidime-resistant Klebsiella pneumoniae

Role of β-Lactamases and Porins in Resistance to Ertapenem and Other β-Lactams in Klebsiella pneumoniae

GA Jacoby, DM Mills, N Chow - Antimicrobial agents and …, 2004 - Am Soc Microbiol
resistance to ertapenem was produced by β-lactamases of groups 1, 2f, and 3 in a strain
of Klebsiella pneumoniae … ACT-1 β-lactamase, ertapenem-resistant mutants for which the …