… loss of Wnt/β-catenin signaling mediated … β-catenin in CD11c + macrophages improved
resolution of bleomycin-induced pulmonary fibrosis confirms an important role of Wnt/β-catenin …

… resolution (3), whereas depletion of the Ly6C lo monocytes caused a failure of fibrosis resolution
in the CCl 4 model of liver fibrosis… the maintenance and resolution of fibrotic disease (6). …

… for fibrosis resolution [62], with these levels sustained during the fibrosis-resolution period,
even … Administration of PRI-724 during the resolution period accelerated fibrosis resolution …

… The failure to resolve acute inflammation leads to chronic inflammation, organ remodeling
and fibrosis with the subsequent deposition of extracellular matrix. β-catenin is involved in the …

… Recently, it was reported that Lrp5/β-catenin signaling activation in lung myeloid cells leads
… the resolution of lung fibrosis. Forced expression of a stabilized β-catenin mutant is able to …

… mouse model in which β-catenin can be selectively deleted in … β-catenin in AECs in lung
repair and protection from fibrosis. … of β-catenin in the alveolar epithelium, resolution of fibrosis …

… pulmonary fibrosis/usual interstitial pneumonia (IPF/UIP), we analyzed the expression patterns
of β-catenin … In 18 of 20 cases of IPF/UIP investigated on serial sections, nuclear β-catenin …

… Wnt/β-catenin/CBP-dependent transcription in a more clinically relevant setting, we next
examined the effect on fibrosis of delayed administration of ICG-001 after resolution of the early …

… did not progress to fibrosis. Signaling through β-catenin has been implicated in EMT; we
found that in primary AECs, α3 integrin was required for β-catenin phosphorylation at tyrosine …

… of another mechanism that contributes to fibrosis resolution, besides the inhibition of quiescent
… the CD11b + F4/80 + Ly6C low macrophage subset is responsible for fibrosis resolution ( …