… Pathophysiology of progression from acute disease to chronic critical illness. The acute
disease is … If inflammation fails to resolve, the persistent disease leads to the development of an …

… In patients suffering from acute critical illness of various etiologies, respiratory muscle
dysfunction is quite frequent and may develop early. Demoule et al. have shown that 64% of …

… in the development of several respiratory diseases. Of these respiratory diseases, it has …
the symptoms and severity of several respiratory diseases, including OSA and asthma. Thus…

… during winter seasons, and to study the association between respiratory viral pathogens …
respiratory viral infection would be associated with both increased mortality and critical illness …

… of critical illness. De-emphasizing syndromes, we focus on the underlying biological changes
that underpin critical illness … We hypothesize that such an approach will accelerate critical …

… Although advances in intensive care have enabled more patients to survive an acute
critical illness, they also have created a large and growing population of chronically critically ill …

… Although infectious diseases remain important causes of respiratory failure, noninfectious
… In addition, the underlying respiratory disease may be worsened as a result of the immune …

… 19 multiorgan dysfunction and is associated with critical illness and mortality in COVID-19 (…
disease severity and risk for both SARS-CoV-2 (100) and COVID-19 (101) respiratory disease…

… In the present study the most common sustained symptoms in patients with chronic
respiratory diseases were pain complaints, which have been also found by other studies in …

… The chronically critically ill (CCI) comprise a rapidly growing population of patients who have
survived acute critical illness, only to be left with ongoing organ dysfunctions requiring high …