Breast cancer response to neoadjuvant chemotherapy: predictive markers and relation with outcome

IF Faneyte, JG Schrama, JL Peterse… - British journal of …, 2003 - nature.com
… of tumour characteristics associated with tumour response and outcome is of great clinical
neoadjuvant chemotherapy. Tumour samples were taken prior to and after chemotherapy. …

Response to neoadjuvant chemotherapy best predicts survival after curative resection of gastric cancer

AM Lowy, PF Mansfield, SD Leach, R Pazdur… - Annals of …, 1999 - journals.lww.com
… phase II trials using neoadjuvant chemotherapy to treat patients … evaluate whether response
to neoadjuvant chemotherapy is … The outcome of such trials will define whether neoadjuvant

Systematic review of randomized and nonrandomized trials of the clinical response and outcomes of neoadjuvant systemic chemotherapy for resectable colorectal …

TC Chua, A Saxena, W Liauw, A Kokandi… - Annals of surgical …, 2010 - Springer
… to determine the response to neoadjuvant chemotherapy and survival outcomes of
patients with resectable CLM, by examining the response to neoadjuvant chemotherapy (radiological …

Pathologic complete response after neoadjuvant chemotherapy and long-term outcomes among young women with breast cancer

L Spring, R Greenup, A Niemierko, L Schapira… - Journal of the National …, 2017 - jnccn.org
… pCR and survival outcomes in young … neoadjuvant chemotherapy (NAC) for stage II–III
invasive breast cancer between 1998 and 2014 at Massachusetts General Hospital. Outcomes

Pathologic complete response after neoadjuvant chemotherapy and impact on breast cancer recurrence and survival: a comprehensive meta-analysis

LM Spring, G Fell, A Arfe, C Sharma, R Greenup… - Clinical cancer …, 2020 - AACR
… treatment, and we notably found this did not further improve outcomes. The results of this
comprehensive meta-analysis overall suggest pCR is a strong surrogate endpoint for TNBC …

Relationship of clinical and pathologic response to neoadjuvant chemotherapy and outcome of locally advanced breast cancer

C Gajdos, PI Tartter, A Estabrook… - Journal of surgical …, 2002 - Wiley Online Library
… treated with neoadjuvant chemotherapy for locally advanced breast cancers found little
evidence that measurable clinical or pathologic changes attributable to chemotherapy predicted …

The response to neoadjuvant chemotherapy predicts clinical outcome and increases breast conservation in advanced breast cancer

PM Spanheimer, JC Carr, A Thomas, SL Sugg… - The American Journal of …, 2013 - Elsevier
… or pathologic responses to neoadjuvant chemotherapy had … with pCR after neoadjuvant
chemotherapy defined patients with … a more pronounced response to neoadjuvant chemotherapy

Response-guided neoadjuvant chemotherapy for breast cancer

G von Minckwitz, JU Blohmer, SD Costa… - Journal of Clinical …, 2013 - ascopubs.org
… Given mounting evidence that breast cancer subtypes differ in their short (pCR 11 )
responses and long-term outcome 12 to cytotoxic treatment, our post hoc statistical approach …

Long-term survival outcomes of advanced gastric cancer patients who achieved a pathological complete response with neoadjuvant chemotherapy: a systematic …

H Cho, J Nakamura, Y Asaumi, H Yabusaki… - Annals of surgical …, 2015 - Springer
… A pathologic complete response (pCR) can sometimes be induced by intensive or long-term
neoadjuvant chemotherapy (NAC). This prognostic research study based on a systematic …

On-treatment biomarkers can improve prediction of response to neoadjuvant chemotherapy in breast cancer

RJ Bownes, AK Turnbull, C Martinez-Perez… - Breast Cancer …, 2019 - Springer
… We have identified AAGAB as a novel on-treatment biomarker for accurate prediction of
pCR and outcome in patients treated with neoadjuvant chemotherapy. A semi-supervised …