Characterizing heterogeneous cellular responses to perturbations

MD Slack, ED Martinez, LF Wu… - Proceedings of the …, 2008 - National Acad Sciences
… characterize the heterogeneous responses of cancer … heterogeneity. Despite the observed
phenotypic diversity of cells observed within our data, low-complexity models of heterogeneity

Analysis of the influence of cell heterogeneity on nanoparticle dose response

MJ Ware, B Godin, N Singh, R Majithia… - ACS …, 2014 - ACS Publications
… role of individual cell heterogeneity in determining this population response, we use high-throughput
microscopy to directly analyze cell-to-cell variability in dose and response. The time …

The link between response time and preference, variance and processing heterogeneity in stated choice experiments

D Campbell, MR Mørkbak, SB Olsen - Journal of Environmental Economics …, 2018 - Elsevier
… the highly equivocal relationship between response time and respondents' choices. …
heterogeneity and explore whether response time helps to explain these three types of heterogeneity

Heterogeneity and cancer

KH Allison, GW Sledge - Oncology, 2014 - go.gale.com
… This intratumor heterogeneity can result in divergent responses to selective pressures,
such that with metastatic progression, different clones can predominate in different metastatic …

Gdp and temperature: Evidence on cross-country response heterogeneity

KA Berg, CC Curtis, NC Mark - European Economic Review, 2024 - Elsevier
… We find substantial heterogeneity across countries in the impulse responses of real GDP per
capita growth to shocks to our temperature components–more than was previously reported …

Intratumoral heterogeneity in cancer progression and response to immunotherapy

I Vitale, E Shema, S Loi, L Galluzzi - Nature medicine, 2021 - nature.com
… considerable genetic, phenotypic, and behavioral heterogeneity in all its components.
Here, we discuss the main sources of intratumoral heterogeneity and its impact on the natural …

Pathogen cell-to-cell variability drives heterogeneity in host immune responses

R Avraham, N Haseley, D Brown, C Penaranda… - Cell, 2015 - cell.com
responses of individual macrophages to invading Salmonella, we find that variation between
individual infected host cells is determined by the heterogeneous … type I IFN responses by …

Local response heterogeneity indexes experience-based neural differentiation in reading

JJ Purcell, B Rapp - Neuroimage, 2018 - Elsevier
heterogeneity of neural responses in this region varies according to the frequency with which
written letter strings have been experienced (consonant strings, pseudowords, low, middle …

Spatial heterogeneity of the nonlinear dynamics in the FMRI BOLD response

RM Birn, ZS Saad, PA Bandettini - Neuroimage, 2001 - Elsevier
… factors and the neuronal response motivates the study of spatial variations in the nonlinearity
of the BOLD signal. In this paper we quantified the spatial heterogeneity of the BOLD signal …

Spatial heterogeneity and functional response: an experiment in microcosms with varying obstacle densities

C Hauzy, T Tully, T Spataro, G Paul, R Arditi - Oecologia, 2010 - Springer
… Spatial heterogeneity of the environment has long been recognized as a major factor in …
responses. By analogy with reaction–diffusion models for chemical systems in heterogeneous