Challenges in liver cancer and possible treatment approaches

D Anwanwan, SK Singh, S Singh, V Saikam… - … BBA)-Reviews on Cancer, 2020 - Elsevier
… vaccines to prevent infection or inflammatory responses, and by non-specific cancer
immunotherapies that provide a general boost to the immune system. In 2013, this field of research …

[PDF][PDF] Correlation between inflammatory cytokines and liver cancer stem cell markers in DEN-induced liver cancer rats

ZH Liu, MJ Bai, JQ Li, SH Yan, XW Ye… - Eur. Rev. Med …, 2021 - europeanreview.org
liver cancer stem cell markers, thereby promoting the occurrence and progression of liver
cancer… MicroRNA expression, survival and response to interferon in liver cancer. N Engl J Med …

Early prediction of response focused on tumor markers in atezolizumab plus bevacizumab therapy for hepatocellular carcinoma

N Tanabe, I Saeki, Y Aibe, T Matsuda, T Hanazono… - Cancers, 2023 - mdpi.com
… treatment response. Tumor markers are useful in predicting treatment response and prognosis.
… The staging was based on the Barcelona Clinic Liver Cancer (BCLC) staging system [4]. …

Biomarkers and genetic markers of hepatocellular carcinoma and cholangiocarcinoma—what do we already know

J Baj, Ł Bryliński, F Woliński, M Granat, K Kostelecka… - Cancers, 2022 - mdpi.com
liver cancer with an increasing worldwide mortality rate. Cholangiocarcinoma (CCA) is the
second most common primary liver cancer… to a lack or to a poor response to the treatment [48]. …

AFP, AFP-L3, DCP, and GP73 as markers for monitoring treatment response and recurrence and as surrogate markers of clinicopathological variables of HCC

K Yamamoto, H Imamura, Y Matsuyama… - Journal of …, 2010 - Springer
Marker values of these 77 patients 1 month post-surgery … of tumor markers to reflect the
therapeutic response after curative … proposed by the Liver Cancer Study Group of Japan [16]. …

Identification of liver cancer progenitors whose malignant progression depends on autocrine IL-6 signaling

G He, D Dhar, H Nakagawa, J Font-Burgada, H Ogata… - Cell, 2013 - cell.com
… This is especially important in cancers of the liver and pancreas, which … markers such as
α fetoprotein (AFP), glypican 3 (Gpc3), and Ly6D, whose expression in mouse liver cancer

Serum markers of hepatocellular carcinoma

G Malaguarnera, M Giordano, I Paladina… - Digestive diseases and …, 2010 - Springer
… of liver function and tumor characteristics to establish a prognosis for HCC patients, and patients
are followed-up to monitor the response to … , indicates a favorable response to treatment. …

CD13 is a therapeutic target in human liver cancer stem cells

N Haraguchi, H Ishii, K Mimori… - The Journal of …, 2010 - Am Soc Clin Investig
… Here, we have demonstrated that CD13 is a marker for semiquiescent CSCs in human liver
cancer cell lines and clinical samples and that targeting these cells might provide a way to …

Early tumor marker response predicts treatment outcomes in patients with unresectable hepatocellular carcinoma receiving combined lenvatinib, immune checkpoint …

MC Luo, JY Wu, JY Wu, ZT Lin, YN Li… - Journal of …, 2023 - Taylor & Francis
… Therefore, this study explored the clinical utility of early AFP and DCP responses as …
The primary endpoint of this study was ORR, assessed according to the modified Response

… of patients presenting with elevated tumor marker levels but negative gadoxetic acid-enhanced liver MRI after a complete response to hepatocellular carcinoma …

KE Kim, DH Sinn, MS Choi, H Kim - Plos one, 2022 - journals.plos.org
response after treatment. This study was aimed to assess the clinical outcome of HCC
patients who had achieved a complete response but later presented with elevated tumor marker