The role of endoplasmic reticulum stress in diabetic nephropathy

Y Fan, K Lee, N Wang, JC He - Current diabetes reports, 2017 - Springer
Diabetic nephropathy (DN) has become the leading cause of … suggests that endoplasmic
reticulum (ER) stress plays a major … knowledge on the role of ER stress in the setting of kidney …

Crosstalk between endoplasmic reticulum stress and oxidative stress in the progression of diabetic nephropathy

P Victor, D Umapathy, L George, U Juttada… - Cell Stress and …, 2021 - Springer
diabetic nephropathy. In this present study, we studied the crosstalk between the endoplasmic
reticulum stress and oxidative stress … isomerase and endoplasmic reticulum oxidase 1α, a …

Attenuation of diabetic nephropathy in diabetes rats induced by streptozotocin by regulating the endoplasmic reticulum stress inflammatory response

W Qi, J Mu, ZF Luo, W Zeng, YH Guo, Q Pang, ZL Ye… - Metabolism, 2011 - Elsevier
Diabetic nephropathy (DN) has become the principal cause of end-stage renal disease in
the Western world and a major cause of morbidity and mortality from diabetic complications [1], …

Endoplasmic reticulum stress in the diabetic kidney, the good, the bad and the ugly

R Cunard - Journal of clinical medicine, 2015 - mdpi.com
… goal of identifying therapeutic strategies that will improve outcomes in diabetic nephropathy.
… The development of diabetic nephropathy is influenced by a number of factors including …

The endoplasmic reticulum stress response and diabetic kidney disease

R Cunard, K Sharma - American journal of physiology-renal …, 2011 - journals.physiology.org
… PBA attenuates manifestations of diabetic nephropathy including markers of renal oxidative
… of ER stress in regulating efficient secretory cell function (30, 119). Diabetic nephropathy is …

Endoplasmic reticulum stress in diabetic nephrology: regulation, pathological role, and therapeutic potential

L Ni, C Yuan, X Wu - Oxidative medicine and cellular longevity, 2021 - Wiley Online Library
reticulum (ER) stress in the development and pathogenesis of diabetic nephropathy (DN).
Hyperglycemia induces ER stress and apoptosis in renal cells. The induction of ER …

Apoptosis induced by endoplasmic reticulum stress involved in diabetic kidney disease

G Liu, Y Sun, Z Li, T Song, H Wang, Y Zhang… - … and biophysical research …, 2008 - Elsevier
… However, whether it is involved in the renal injury of diabetic nephropathy is still not
known. We investigated the involvement of ER-associated apoptosis in kidney disease of …

Endoplasmic reticulum stress contributes to pyroptosis through NF-κB/NLRP3 pathway in diabetic nephropathy

Q Li, K Zhang, L Hou, J Liao, H Zhang, Q Han, J Guo… - Life Sciences, 2023 - Elsevier
… by ER stress leading to pyroptosis in diabetic nephropathy. Therefore, our … reticulum stress
leading to pyroptosis is the main mechanism of hyperglycemia-induced diabetic nephropathy

[HTML][HTML] Induction of diabetes in aged C57B6 mice results in severe nephropathy: an association with oxidative stress, endoplasmic reticulum stress, and inflammation

J Wu, R Zhang, M Torreggiani, A Ting, H Xiong… - The American journal of …, 2010 - Elsevier
stress in diabetic nephropathy, 5-month-old female C/EBP homologous protein (CHOP)-deficient
mice, obtained from The Jackson Laboratory (Bar Harbor, ME) were also made diabetic

[PDF][PDF] Stress in the kidney is the road to pERdition: is endoplasmic reticulum stress a pathogenic mediator of diabetic nephropathy

A Zhuang, JM Forbes - J Endocrinol, 2014 - Citeseer
… the role of ER stress in specific resident kidney cells and how this may be integral in the
pathogenesis and progression of diabetic nephropathy (DN). Given that diabetes is a perturbed …