Endoplasmic reticulum stress and lipid metabolism: mechanisms and therapeutic potential
S Basseri, RC Austin - Biochemistry research international, 2012 - Wiley Online Library
… stress/UPR activation plays a critical role in lipid metabolism … ER-stress-dependent
dysregulation of lipid metabolism may … ER stress/UPR signalling pathways play in regulation of …
dysregulation of lipid metabolism may … ER stress/UPR signalling pathways play in regulation of …
The role of ER stress in lipid metabolism and lipotoxicity
J Han, RJ Kaufman - Journal of lipid research, 2016 - ASBMB
… reticulum (ER) is a cellular organelle important for regulating calcium homeostasis, lipid
metabolism, … protein and activated by proteolysis in response to endoplasmic reticulum stress. …
metabolism, … protein and activated by proteolysis in response to endoplasmic reticulum stress. …
[HTML][HTML] Lipophagy mediated carbohydrate-induced changes of lipid metabolism via oxidative stress, endoplasmic reticulum (ER) stress and ChREBP/PPARγ …
… and HG-induced changes of lipid metabolism were via enhancing … changes of lipid metabolism
by oxidative stress and ER stress, … and lipid metabolism via ChREBP/PPARγ pathway. …
by oxidative stress and ER stress, … and lipid metabolism via ChREBP/PPARγ pathway. …
The role of endoplasmic reticulum in hepatic lipid homeostasis and stress signaling
S Fu, SM Watkins, GS Hotamisligil - Cell metabolism, 2012 - cell.com
… Lipid metabolism occurs primarily at the ER, where many of the enzymes involved in
intermediary and complex lipid metabolism reside, giving the ER a central but under-investigated …
intermediary and complex lipid metabolism reside, giving the ER a central but under-investigated …
[HTML][HTML] A guide to understanding endoplasmic reticulum stress in metabolic disorders
IL Lemmer, N Willemsen, N Hilal, A Bartelt - Molecular metabolism, 2021 - Elsevier
… Therefore, disturbances in proteostasis, for example, will impact lipid metabolism in the
ER and vice versa. This is especially true in obesity, where continuous metabolic pressure …
ER and vice versa. This is especially true in obesity, where continuous metabolic pressure …
[HTML][HTML] Aberrant lipid metabolism disrupts calcium homeostasis causing liver endoplasmic reticulum stress in obesity
… defects, reduce ER stress and improve metabolism, supporting the hypothesis that changes
in lipid metabolism contribute to SERCA dysfunction, ER stress and hyperglycaemia in both …
in lipid metabolism contribute to SERCA dysfunction, ER stress and hyperglycaemia in both …
Role of endoplasmic reticulum stress in hepatic glucose and lipid metabolism and therapeutic strategies for metabolic liver disease
W Zheng, Q Sun, L Li, Y Cheng, Y Chen, M Lv… - International …, 2022 - Elsevier
… Endoplasmic reticulum stress plays a very important role in … and lipid metabolism and
discusses the mechanism linking endoplasmic reticulum stress with glucose and lipid metabolism …
discusses the mechanism linking endoplasmic reticulum stress with glucose and lipid metabolism …
[HTML][HTML] Endoplasmic reticulum stress affects lipid metabolism in atherosclerosis via CHOP activation and over-expression of miR-33
… reticulum (ER) stress is an important event in atherosclerosis. Recent studies have shown
that ER stress deregulates cholesterol metabolism via … ER stress and lipid metabolism and to …
that ER stress deregulates cholesterol metabolism via … ER stress and lipid metabolism and to …
Mitochondrial dysfunction, through impaired autophagy, leads to endoplasmic reticulum stress, deregulated lipid metabolism, and pancreatitis in animal models
G Biczo, ET Vegh, N Shalbueva, OA Mareninova… - Gastroenterology, 2018 - Elsevier
… We find deregulation of acinar cell lipid metabolism in AP. The impaired autophagy, ER
stress, and deregulated lipid metabolism are all mediated by mitochondrial dysfunction and …
stress, and deregulated lipid metabolism are all mediated by mitochondrial dysfunction and …
Endoplasmic reticulum stress and lipid dysregulation
SM Colgan, AA Al-Hashimi, RC Austin - Expert reviews in molecular …, 2011 - cambridge.org
… These findings suggest that caspase-3 or other caspases might function independently of
apoptotic cell death and have a role in cellular lipid metabolism. Although ER …
apoptotic cell death and have a role in cellular lipid metabolism. Although ER …
相关搜索
- endoplasmic reticulum stress lipid metabolism
- role of er stress lipid metabolism
- oxidative stress lipid metabolism
- hepatic lipid metabolism
- protein response lipid metabolism
- aberrant lipid metabolism reticulum stress
- liver disease lipid metabolism
- chop activation lipid metabolism in atherosclerosis
- macrophage lipid chaperone reticulum stress
- impaired autophagy deregulated lipid metabolism
- aberrant lipid metabolism calcium homeostasis
- mitochondrial dysfunction deregulated lipid metabolism
- therapeutic potential lipid metabolism
- therapeutic strategies lipid metabolism
- animal models deregulated lipid metabolism
- endoplasmic reticulum stress lipid accumulation