[HTML][HTML] Endoplasmic reticulum stress and therapeutic strategies in metabolic, neurodegenerative diseases and cancer
S Yuan, D She, S Jiang, N Deng, J Peng, L Ma - Molecular Medicine, 2024 - Springer
… Consequently, therapeutic strategies targeting ER stress-related interventions have attracted
… ER stress in cancer, metabolic, and neurodegenerative diseases, offering novel therapeutic …
… ER stress in cancer, metabolic, and neurodegenerative diseases, offering novel therapeutic …
[HTML][HTML] … dysfunction and endoplasmic reticulum stress in age related macular degeneration, role in pathophysiology, and possible new therapeutic strategies
V Bilbao-Malavé, J González-Zamora, M de la Puente… - Antioxidants, 2021 - mdpi.com
… In this review, we explain how mitochondrial dysfunction and endoplasmic reticulum stress
participate in AMD pathogenesis. We also discuss a role of several antioxidants (bile acids, …
participate in AMD pathogenesis. We also discuss a role of several antioxidants (bile acids, …
Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities
I Kim, W Xu, JC Reed - Nature reviews Drug discovery, 2008 - nature.com
… Given the documented role for CHOP in brain ischaemia, neutralizing this transcription
factor is an attractive therapeutic strategy. As p38 MAPK augments CHOP activity, small-molecule …
factor is an attractive therapeutic strategy. As p38 MAPK augments CHOP activity, small-molecule …
Targeting the endoplasmic reticulum-stress response as an anticancer strategy
… cells suggesting that inducing secretory stress by perturbing intracellular protein trafficking
may be an effective therapeutic strategy. However, as hallmarks of ER stress such as XBP1 …
may be an effective therapeutic strategy. However, as hallmarks of ER stress such as XBP1 …
The role of endoplasmic reticulum stress in human pathology
SA Oakes, FR Papa - Annual Review of Pathology: Mechanisms …, 2015 - annualreviews.org
… of the UPR as a therapeutic strategy to combat these ER stress–associated pathologies. …
of the UPR as a therapeutic strategy to combat these ER stress–associated pathologies. …
of the UPR as a therapeutic strategy to combat these ER stress–associated pathologies. …
Role of endoplasmic reticulum stress in hepatic glucose and lipid metabolism and therapeutic strategies for metabolic liver disease
W Zheng, Q Sun, L Li, Y Cheng, Y Chen, M Lv… - International …, 2022 - Elsevier
… reticulum, the excessive accumulation of misfolded proteins leads to endoplasmic reticulum
stress and … Hepatocytes contain an abundance of smooth and rough endoplasmic reticulum, …
stress and … Hepatocytes contain an abundance of smooth and rough endoplasmic reticulum, …
Endoplasmic reticulum stress as a therapeutic target in cardiovascular disease
T Minamino, I Komuro, M Kitakaze - Circulation research, 2010 - Am Heart Assoc
… Thus, therapeutic interventions that target molecules of the UPR component and reduce
ER stress will be promising strategies to treat cardiovascular diseases. In this review, we …
ER stress will be promising strategies to treat cardiovascular diseases. In this review, we …
Momordicacharantia: a new strategic vision to improve the therapy of endoplasmic reticulum stress
W Chin Chong, R Gundamaraju… - Current …, 2017 - ingentaconnect.com
… reticulum stress and oxidative stress on cellular physiology, the involvement of endoplasmic
reticulum stress and oxidative stress … therapeutic strategy is to reduce endoplasmic reticulum …
reticulum stress and oxidative stress … therapeutic strategy is to reduce endoplasmic reticulum …
[HTML][HTML] Endoplasmic reticulum stress: a novel mechanism and therapeutic target for cardiovascular diseases
M Liu, Z Chen, L Chen - Acta Pharmacologica Sinica, 2016 - nature.com
… reticulum stress (ERS) is a condition that is accelerated by accumulation of unfolded/misfolded
proteins after endoplasmic reticulum … , calcium depletion, oxidative stress, DNA damage …
proteins after endoplasmic reticulum … , calcium depletion, oxidative stress, DNA damage …
Endoplasmic reticulum stress signalling–from basic mechanisms to clinical applications
A Almanza, A Carlesso, C Chintha… - The FEBS …, 2019 - Wiley Online Library
… Relieving ER stress ameliorates the disease state associated with lipid metabolism
alterations, suggesting that targeting ER stress might serve as a therapeutic strategy for treating …
alterations, suggesting that targeting ER stress might serve as a therapeutic strategy for treating …
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