Age of rats seriously affects the degree of retinal damage induced by acute high intraocular pressure

C Tan, T Hu, M Peng, S Liu, J Tong… - Current Eye …, 2015 - Taylor & Francis
… whether retinal damage was affected by age of rats in … retina, (1) neurons at the ganglion
cell layer of aged retina were more susceptible to increased IOP; (2) microglia of aged retina

Light history and age-related changes in retinal light damage.

DT Organisciak, RM Darrow, L Barsalou… - … & visual science, 1998 - iovs.arvojournals.org
… the susceptibility of rats to acute intense-light-induced retinal damage as a function of age
and … degeneration than younger animals were, we exposed rats of various ages to intense …

Early retinal damage in experimental diabetes: electroretinographical and morphological observations

Q Li, E Zemel, B Miller, I Perlman - Experimental eye research, 2002 - Elsevier
Age-matched rats raised under similar conditions served as control. The electroretinogram
… of retinal damage in the early stages of diabetes that had been induced in rats by injection of …

Age-related and light-associated retinal changes in Fischer rats.

YL Lai, RO Jacoby, AM Jonas - Investigative ophthalmology & …, 1978 - iovs.arvojournals.org
… Light-induced retinal damage in rats has been well documented. Outer segments of the
photoreceptor cells degenerate first, and the photoreceptor cells are involved later.'7 Lesions are …

Advanced glycation end products (AGEs) co-localize with AGE receptors in the retinal vasculature of diabetic and of AGE-infused rats.

AW Stitt, YM Li, TA Gardiner, R Bucala… - The American journal …, 1997 - ncbi.nlm.nih.gov
AGE-RI and -R2 colocalized strongly with AGEs of vascular … nornal, diabetic, or AGE-infused
rat retinas, and this distribution … damage, we explored AGE localization within the retina after …

Retinal damage by light in rats

WK Noell, VS Walker, BS Kang… - … & Visual Science, 1966 - iovs.arvojournals.org
… The retina of laboratory rats is affected irreversibly by intense … the severity of the light
damage. The effect was very … all that light genuinely damages the rat retina and that it does …

Photoreceptor degeneration in albino rats: dependency on age

WK O'STEEN, KV Anderson… - … Ophthalmology & Visual …, 1974 - iovs.arvojournals.org
… A portion of the results presented in this study substantiate the earlier report by Ballowitz
and Dammrich0 that retinas of young newborn rats are less damaged than those of adult …

Age-related changes in the retinal pigment epithelium of pigmented rats

ML Katz, WG Robison Jr - Experimental eye research, 1984 - Elsevier
… However, albino animals are highly susceptible to retinal damage by visible light (Noell,
Walker. Kang and Berman, 1966; Kuwabara and Gorn, 1968; Lanum, 1978) ; thus it is difficult, to …

Age-related retinal degeneration in animal models of aging: possible involvement of taurine deficiency and oxidative stress

J Militante, JB Lombardini - Neurochemical research, 2004 - Springer
… Also intense light-mediated retinal damage is greater in older SD rats and is associated with
… , there was a significant increase in the aged rat as compared to the control rat cortex. With …

Protection by dimethylthiourea against retinal light damage in rats.

DT Organisciak, RM Darrow, YI Jiang… - … & visual science, 1992 - iovs.arvojournals.org
… in reducing retinal light damage in both types of rats and that, in cyclic light-reared rats,
DMTU … level than did age-matched rats reared in darkness, and they were less susceptible to …