Retinoic acid signaling and neuronal differentiation

A Janesick, SC Wu, B Blumberg - Cellular and Molecular Life Sciences, 2015 - Springer
retinoic acid (RA). The ability of RA to induce post-mitotic, neural phenotypes in various stem
cells, in vitro, served as early evidence … There is growing evidence that bona fide RARs are …

Retinoic acid and development of the central nervous system

M Maden, N Holder - BioEssays, 1992 - Wiley Online Library
… In this article we consider the evidence that the developing … The kinds of evidence that
support this contention are, firstly, … Summary We consider the evidence that RAT, the vitamin A …

Retinoic acid in the development, regeneration and maintenance of the nervous system

M Maden - Nature Reviews Neuroscience, 2007 - nature.com
Retinoic acid (RA) is involved in the induction of neural differentiation, motor neuron axon
outgrowth and neural patterning during development, but there is growing evidence that RA …

Retinoic acid and affective disorders: the evidence for an association

JD Bremner, KD Shearer… - The Journal of clinical …, 2011 - psychiatrist.com
retinoic acid.9 It is the all-trans isomer of retinoic acid that has a high affinity for the retinoic
acid … via isomerization in tissue to all-trans retinoic acid.10,11 Although this implies the activity …

Retinoic acid and depressive disorders: evidence and possible neurobiological mechanisms

P Hu, AM van Dam, Y Wang, PJ Lucassen… - … & Biobehavioral Reviews, 2020 - Elsevier
… like 13-cis-retinoic acid (ITT) and all-trans retinoic acid (ATRA), are … clinical evidences
supporting association between retinoids … Clinical evidences include case reports and studies …

[HTML][HTML] Retinoic acid receptors at 35 years

M Petkovich, P Chambon - Journal of Molecular …, 2022 - jme.bioscientifica.com
… This review is about the discovery of specific receptors for the vitamin A derivative, retinoic
acid (RA), which launched extensive molecular, genetic, and structural investigations into …

Retinoic acid in alveolar development, maintenance and regeneration

M Maden, M Hind - … Transactions of the Royal Society of …, 2004 - royalsocietypublishing.org
… Recent data suggest that exogenous retinoic acid (RA), the … We provide evidence that
RA is required during … cellular retinoic acid binding protein II and the retinoic acid-depen…

The emerging role of retinoids and retinoic acid metabolism blocking agents in the treatment of cancer

WH Miller Jr - … International Journal of the American Cancer …, 1998 - Wiley Online Library
… associated with exogenous retinoids has been to increase the levels of endogenous retinoic
acid (RA… There is evidence that RAR expression is higher in retinoid-sensitive human breast …

[HTML][HTML] Retinoic acid, CYP26, and drug resistance in the stem cell niche

S Alonso, RJ Jones, G Ghiaur - Experimental Hematology, 2017 - Elsevier
… first association between retinoic RA and hematopoiesis [40]. Definitive evidence emerged
almost … Growing evidence suggests that RA signaling may be regulated differentially between …

Role of retinoic acid in the differentiation of embryonal carcinoma and embryonic stem cells

DR Soprano, BW Teets, KJ Soprano - Vitamins & hormones, 2007 - Elsevier
Retinoic acid (RA), the most potent natural form of vitamin A, plays an important role in
many diverse biological processes such as embryogenesis and cellular differentiation. This …