Talking convergence: growing evidence links FOXP2 and retinoic acid in shaping speech-related motor circuitry

M Negwer, D Schubert - Frontiers in neuroscience, 2017 - frontiersin.org
… The canonical cortico-basal-ganglia-thalamic motor circuit is thought to be crucial for the
motor aspects of vocal production. Interestingly, in this canonical circuit FoxP2 (refers to the …

Retinoic acid signaling at sites of plasticity in the mature central nervous system

G Thompson Haskell, TM Maynard… - Journal of …, 2002 - Wiley Online Library
We used transgenic reporter mice to determine whether brain regions that respond to retinoic
acid (RA) during development do so in maturity. We focused on two prominent sites of …

[HTML][HTML] Regulation of prefrontal patterning and connectivity by retinoic acid

M Shibata, K Pattabiraman, B Lorente-Galdos… - Nature, 2021 - nature.com
… that retinoic acid signalling through the retinoic acid receptors … patterning of prefrontal and
motor areas, development of PFC–… in frontal lobe patterning and circuit development. Many of …

Retinoic acid signaling: A new piece in the spoken language puzzle

JR Van Rhijn, SC Vernes - Frontiers in Psychology, 2015 - frontiersin.org
Retinoic acid … the motor circuitry, including cortical, striatal, and multiple thalamic regions
(Krezel et al., 1999), (Figure 1B). We focus on two key receptors found in the motor circuitry: …

Retinoic acid and hindbrain patterning

JC Glover, JS Renaud, FM Rijli - Journal of neurobiology, 2006 - Wiley Online Library
… signaling plays in the specification of different neuron types and the circuits they participate
in… Patterning of motor neurons by retinoic acid in the chick embryo hindbrain in vitro. Mol Cell …

Modular patterning of structure and function of the striatum by retinoid receptor signaling

WL Liao, HC Tsai, HF Wang, J Chang… - Proceedings of the …, 2008 - National Acad Sciences
… levels of retinoic acid were spatiotemporally … neural circuits and perhaps change of dopamine
tone within the basal ganglia, which in turn leads to altered drug-induced repetitive motor

Retinoic acid induces changes in electrical properties of adult neurons in a dose-and isomer-dependent manner

ND Vesprini, GE Spencer - Journal of neurophysiology, 2014 - journals.physiology.org
… of retinoic acid to modify the electrical activity of neurons. In this study, we determined whether
retinoic acid might … of retinoic acid can rapidly elicit changes in neuronal firing properties. …

Roles of retinoic acid signaling in shaping the neuronal architecture of the developing amphioxus nervous system

E Zieger, S Candiani, G Garbarino, JC Croce… - Molecular …, 2018 - Springer
… possesses only a single retinoic acid receptor (rar) and a single retinoid X receptor (rxr) gene,
… of RA signaling for the acquisition of motor control in amphioxus larvae, which we propose …

Retinoic acid functions as a key GABAergic differentiation signal in the basal ganglia

C Chatzi, T Brade, G Duester - PLoS biology, 2011 - journals.plos.org
… generation of motor neurons both in the hindbrain and spinal cord, but the role of retinoic acid
in … GABAergic interneurons are inhibitory local circuit neurons modulating neuronal activity …

Retinoic acid supplementation ameliorates motor incoordination via RARα-CBLN2 in the cerebellum of a prenatal valproic acid-exposed rat autism model

B Yuan, L Luo, C Hu, F Lin, T Yang, J Chen, T Li - Neuroscience Letters, 2023 - Elsevier
… demonstrated both abnormal motor coordination and … of retinoic acid (RA) synthesis enzymes
(RDH10, ALDH1A1), metabolic enzyme (CYP26A2), and lower levels of RA, retinoic acid