A retrospective analysis of pharmacokinetic-pharmacodynamic parameters as indicators of the clinical efficacy of ceftizoxime

A Sánchez-Navarro, CI Colino… - Clinical …, 2001 - Springer
Analysis of the correlation between the values taken by these parameters and the … for
antimicrobial dosage optimisation. With this in mind, we were prompted to conduct a retrospective

Omitted doses as an unintended consequence of a hospital restricted antibacterial system: a retrospective observational study

N Powell, BD Franklin, A Jacklin… - Journal of Antimicrobial …, 2015 - academic.oup.com
… episode we randomly selected one of these for analysis. We calculated ORs and their
CIs for the risk of an omitted first dose. Our primary analysis focused on restriction and ward-stock …

Correlation of vancomycin dosing to serum concentrations in pediatric patients: a retrospective database review

KW Benner, MA Worthington… - The Journal of …, 2009 - meridian.allenpress.com
antimicrobial dosing maximizes therapeutic benefit while minimizing development of
antimicrobial … Common pediatric references recommend vancomycin dosing of 40 mg/kg/day …

[HTML][HTML] Optimal timing for antimicrobial prophylaxis to reduce surgical site infections: a retrospective analysis of 531 patients

C Paasch, C Schildberg, S Lünse, S Heisler, J Meyer… - Scientific Reports, 2023 - nature.com
… statistical power than those of our retrospective analysis. But the study groups were not
exactly comparable to our patients in terms of AP timing, doses, and AP regimens. Unfortunately, …

[HTML][HTML] Antimicrobial Stewardship and Dose Adjustment of Restricted Antimicrobial Drugs in Hospital Setting

I Vlak, I Samardžić, I Marinović, N Bušić, VB Vrca - Pharmacy, 2023 - mdpi.com
antimicrobial drugs that required dose adjustment according to renal function. A retrospective
This study analyzed requests for restricted antimicrobial drugs (n = 2890) during a 3-month …

Retrospective study of prolonged versus intermittent infusion piperacillin-tazobactam and meropenem in intensive care unit patients at an academic medical center

RJ Dow, WE Rose, BC Fox, JM Thorpe… - Infectious Diseases in …, 2011 - journals.lww.com
antimicrobial resistance and a shortage of novel antimicrobial development, new dosing
In this retrospective analysis of a newly implemented prolonged infusion strategy, we …

Optimization of antimicrobial dosing in patients with acute kidney injury: a single-centre observational study

S Hughes, KL Heard, N Mughal… - JAC-antimicrobial …, 2022 - academic.oup.com
Antimicrobial dosing within this study shows a high adherence to local guidelines
recommending unadjusted antimicrobial dosing … The retrospective analysis is insufficient to link …

Teicoplanin therapeutic drug monitoring in critically ill patients: a retrospective study emphasizing the importance of a loading dose

F Pea, L Brollo, P Viale, F Pavan… - Journal of Antimicrobial …, 2003 - academic.oup.com
… In this study, we have analysed, retrospectively, results from the TDM of teicoplanin carried
… Unfortunately, because this was a retrospective analysis, not all patients were sampled on …

Clinical outcomes of temocillin use for invasive Enterobacterales infections: a single-centre retrospective analysis

KL Heard, K Killington, N Mughal… - JAC-Antimicrobial …, 2021 - academic.oup.com
… The EUCAST breakpoint (2020) 16 recommendations advising dosing at 6 g/day to cover
pathogens with MIC 0.001–16 mg/L instigated this retrospective analysis, yet we find dosing at …

[HTML][HTML] The effect of inadequate initial empiric antimicrobial treatment on mortality in critically ill patients with bloodstream infections: a multi-centre retrospective …

RD Savage, RA Fowler, AH Rishu, SM Bagshaw… - PLoS …, 2016 - journals.plos.org
… A retrospective cohort study was conducted across 13 intensive care units in Canada. We …
as not receiving at least one dose of an antimicrobial to which the causative pathogen(s) was …