Reversal agents for direct oral anticoagulants: considerations for hospital physicians and intensivists

NR Desai, D Cornutt - Hospital Practice, 2019 - Taylor & Francis
… prohemostatic agents can counteract the anticoagulant action of DOACs in emergency
situations, when specific reversal agents are unavailable. However, specific reversal agents are …

National survey of the use of sedating drugs, neuromuscular blocking agents, and reversal agents in the intensive care unit

DH Rhoney, KR Murry - Journal of intensive care medicine, 2003 - journals.sagepub.com
… to 25 of the nursing staff, physicians, and pharmacists in the ICU at … Differences in sedative,
NMBA, and reversal agents use … The frequency of use of the agents based on type of hospital

Reversal agents for the new generation of oral anticoagulants: implications for the Perioperative physician

GM Lohrmann, D Atwal, JG Augoustides… - … of Cardiothoracic and …, 2016 - jcvaonline.com
… rapid reversal agents in urgent clinical scenarios. Idarucizumab has been approved commercially
for acute reversal of … More candidate agents are in preclinical trials. It is likely that more …

Reversal agents for the direct oral anticoagulants

JE Ansell - Hematology/Oncology Clinics, 2016 - hemonc.theclinics.com
agent have any deleterious side effects of its own, will reversal of anticoagulation place the
patient at an undue risk of a thrombotic event, and will the reversal agent be expensive and …

Anticoagulant reversal strategies in the emergency department setting: recommendations of a multidisciplinary expert panel

CW Baugh, M Levine, D Cornutt, JW Wilson… - Annals of emergency …, 2020 - Elsevier
agents and variety of anticoagulants with different mechanisms of action, pharmacokinetics,
indications, and corresponding reversal agents increase, physicians … by hospital resources …

Anticoagulant and antiplatelet medications encountered in emergency surgery patients: a review of reversal strategies

JL Gordon, TC Fabian, MD Lee… - Journal of Trauma and …, 2013 - journals.lww.com
… /antiplatelet agents and their reversal agents in … Reversal management for each agent is
briefly mentioned in this section and discussed further in the Pharmacology of Reversal Agents

Analysis of anticoagulation reversal survey (ARES)

AS Rowe, S Dietrich, LA Hamilton - Hospital Practice, 2020 - Taylor & Francis
… The type of reversal agent utilized was compared for the type of hospital, country region,
and type of ordering physician. In addition, pharmacists were asked to rank their involvement …

Novel oral anticoagulants and reversal agents: considerations for clinical development

TC Sarich, JH Seltzer, SD Berkowitz, JT Curnutte… - American Heart …, 2015 - Elsevier
… pathway option that could enable earlier availability of NOAC reversal agents for the
benefit of both patients and physicians. Additional clinical studies might be recommended for …

[HTML][HTML] Reversal agents for oral anticoagulant-associated major or life-threatening bleeding

M Moia, A Squizzato - Internal and emergency medicine, 2019 - Springer
… , especially in situations where a specific reversal agent is not available. The choice between
… , they should only be administered by physicians experienced in their use and in bleeding …

A 1-year drug utilization evaluation of protamine in hospitalized patients to identify possible future roles of heparin and low molecular weight heparin reversal agents

CE Mahan - Journal of thrombosis and thrombolysis, 2014 - Springer
… Availability of new reversal agents for approved … hospital in order to determine the
need for a novel reversing … not reversed with protamine due to physician preference and …