Reverse remodeling in heart failure—mechanisms and therapeutic opportunities

N Koitabashi, DA Kass - Nature Reviews Cardiology, 2012 - nature.com
… Here, we review the current evidence for reverse remodeling by … reverse remodeling by
existing therapies, and provide an outlook on promising novel approaches to reverse remodeling

Reverse remodeling in systolic heart failure

T Saraon, SD Katz - Cardiology in review, 2015 - journals.lww.com
… the LV remodeling process. In this article, we review selected studies that demonstrate the
LV reverse remodeling … to effect reverse remodeling may further improve clinical outcomes in …

Reverse remodeling in heart failure–fact or fiction?

B Pieske - European Heart Journal Supplements, 2004 - academic.oup.com
… of development and progression of heart failure, and how therapy … Remodeling and reverse
remodeling The progression of heart failure is associated with left ventricular remodeling, …

Reversing chronic remodeling in heart failure

JO Mudd, DA Kass - Expert review of cardiovascular therapy, 2007 - Taylor & Francis
… For the purpose of this review, we use the original definition of reverse remodeling – that is,
a process where failing hearts can now function at smaller chamber volumes (particularly end…

Myocardial reverse remodeling

JL Hellawell, KB Margulies - Cardiovascular therapeutics, 2012 - Wiley Online Library
… to chamber volume, and other shape changes that can affect pump function, energy utilization,
and the risk of unfavorable clinical sequelae including valvular dysfunction, heart failure (…

Reverse cardiac remodeling and ARNI therapy

A Abboud, JL Januzzi - Current heart failure reports, 2021 - Springer
… As the central process in heart failure, remodeling serves as a pivotal point upon which … of
heart failure with reduced ejection fraction (HFrEF) prominently includes adverse remodeling

[HTML][HTML] Left ventricular reverse remodeling in heart failure: remission to recovery

J Boulet, MR Mehra - Structural Heart, 2021 - Elsevier
… and reverse remodeling are complex and differ in many ways from remodeling processes …
Similarly, we shall not discuss the syndrome of heart failure with preserved ejection fraction …

[HTML][HTML] Redefining reverse remodeling: can echocardiography refine our ability to assess response to heart failure treatments?

AA Waring, SE Litwin - Journal of the American College of Cardiology, 2016 - jacc.org
… causes of heart failure (HF) (5). The concept of reverse remodeling was developed to explain
… increases in EF and evidence of reverse remodeling, defined primarily as reduction in LV …

Reverse remodelling and myocardial recovery in heart failure

GH Kim, N Uriel, D Burkhoff - Nature Reviews Cardiology, 2018 - nature.com
… In this Review, we summarize the latest findings on reverse remodelling and … heart failure,
in particular in the transcriptome, metabalome, and extracellular matrix, persist in the reverse-…

Myocardial reverse remodeling: how far can we rewind?

PG Rodrigues, AF Leite-Moreira… - … of Physiology-Heart …, 2016 - journals.physiology.org
… “remodeling,” “reverse remodeling” also became associated with any alteration in HF that
could be chronically reversed … of heart failure with reduced ejection fraction (HFrEF) and heart