Enhancing the biological relevance of machine learning classifiers for reverse vaccinology
AI Heinson, Y Gunawardana, B Moesker… - International journal of …, 2017 - mdpi.com
… The most biologically relevant classifier generated in this study was built upon the dataset
designated BPAD200+N+B+AF (Figure 2). The top 10 features used by this classifier may be …
designated BPAD200+N+B+AF (Figure 2). The top 10 features used by this classifier may be …
[PDF][PDF] The reverse vaccinology-A contextual overview
… This candidate vaccine is an extensively scrutinized plethora based on the concept of
reverse vaccinology (RV) with special attention reserved for exported targets, generating …
reverse vaccinology (RV) with special attention reserved for exported targets, generating …
Lessons from Reverse Vaccinology for viral vaccine design
L Bruno, M Cortese, R Rappuoli, M Merola - Current opinion in virology, 2015 - Elsevier
… Although almost 15 years have passed since the birthdate of Reverse Vaccinology (RV), …
based approach (Structural Vaccinology [SV]), synthetic biology and some examples of their …
based approach (Structural Vaccinology [SV]), synthetic biology and some examples of their …
Vaccines, reverse vaccinology, and bacterial pathogenesis
I Delany, R Rappuoli, KL Seib - Cold Spring …, 2013 - perspectivesinmedicine.cshlp.org
… Advances in genomics and innovative strategies such as reverse vaccinology have …
increase our fundamental understanding of pathogen biology, mechanisms responsible for the …
increase our fundamental understanding of pathogen biology, mechanisms responsible for the …
Reverse vaccinology in the 21st century: improvements over the original design
C Donati, R Rappuoli - Annals of the New York Academy of …, 2013 - Wiley Online Library
… The term reverse vaccinology originates from the change in perspective allowed by the
advancements in sequencing technologies. The entire genome of the virulent MC58 strain was …
advancements in sequencing technologies. The entire genome of the virulent MC58 strain was …
The development of a vaccine against meningococcus B using reverse vaccinology
V Masignani, M Pizza, ER Moxon - Frontiers in immunology, 2019 - frontiersin.org
… In addition, estimates of protection, based on WGS, hSBA, and MATS, indicate that a proportion
of strains lack a biologically relevant match to the antigens in the vaccine. As an example…
of strains lack a biologically relevant match to the antigens in the vaccine. As an example…
Reverse vaccinology: developing vaccines in the era of genomics
A Sette, R Rappuoli - Immunity, 2010 - cell.com
… , reverse vaccinology has made possible studies on antigen function, leading to an understanding
of the biology of … screening for protective antigens by reverse vaccinology, it was found …
of the biology of … screening for protective antigens by reverse vaccinology, it was found …
Comparison of open-source reverse vaccinology programs for bacterial vaccine antigen discovery
… In the square is highlighted the Reverse Vaccinology part (A). Timeline of the delivery of
RV standalone programs and their main characteristics in terms of type of software, interface …
RV standalone programs and their main characteristics in terms of type of software, interface …
Vaccine types and reverse vaccinology
AN Oli, AB Rowaiye - Vaccinology and methods in vaccine research, 2022 - Elsevier
Vaccinology is a relatively recent discipline involving vaccine development and use. It includes
immunology and infectious illnesses, epidemiology, public health, and pediatrics among …
immunology and infectious illnesses, epidemiology, public health, and pediatrics among …
[PDF][PDF] Review On Application Of Reverse Vaccinology For Dangerous Pathogens
H Mulatu - academia.edu
… paper show development of reverse vaccinology, their relevance, and … Reverse vaccinology
presents a revolution in both immunology and biotechnology and shows how a biological …
presents a revolution in both immunology and biotechnology and shows how a biological …
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