Nasal clearance in rhesus monkeys

RK Wolff, DL Allen, BL Hughes, M Osier… - Journal of aerosol …, 1993 - liebertpub.com
… ml (100 mCi) was accomplished by inserting the wand 1.5 cm into the nasal cavity of the
left nostril and applying 30 psi of compressed air for 0.5 sec using an automated timed pump. …

Studies of inspiratory airflow patterns in the nasal passages of the F344 rat and rhesus monkey using nasal molds: relevance to formaldehyde toxicity

KT Morgan, JS Kimbell, TM Monticello, AL Patra… - Toxicology and applied …, 1991 - Elsevier
… of nasal lesions in rats and rhesus monkeys following inhalation … are a consequence of nasal
airflow characteristics. Inspiratory … nasal cavity of the rhesus monkey differed significantly in …

Effect of delivery devices on nasal deposition and mucociliary clearance in rhesus monkeys

BL Hughes, DL Allen, MA Dorato… - Aerosol science and …, 1993 - Taylor & Francis
… nasally administered drugs on the nasal mucosa, which in turn … Monkeys would appear to
be an appropriate animal model to … that might be useful in humans because the nasal cavity of …

Computer simulation of inspiratory nasal airflow and inhaled gas uptake in a rhesus monkey

GM Kepler, RB Richardson, KT Morgan… - Toxicology and applied …, 1998 - Elsevier
The nasal cavity of the rhesus monkey consisted of two airways separated by a septum,
which was roughly planar. The septum extended 71.5 mm from the tip of the nostrils to the …

Effects of formaldehyde gas on the respiratory tract of rhesus monkeys. Pathology and cell proliferation.

TM Monticello, KT Morgan, JI Everitt… - The American journal of …, 1989 - ncbi.nlm.nih.gov
… The rhesus monkey (Macaca mulatta) was selected for the … of the nasal cavity of the rhesus
monkey and man.19-21 A comparison of nasal casts and transverse sections of the nasal

Intranasal monoclonal IgA antibody to respiratory syncytial virus protects rhesus monkeys against upper and lower respiratory tract infection

R Weltzin, V Traina-Dorge, K Soike… - Journal of Infectious …, 1996 - academic.oup.com
… Studies in humans show that substances applied to the nasal mucosa are largely cleared by
… detected in nasal swab specimens of rhesus monkeys for days after intranasal application. …

Covalent binding of inhaled formaldehyde to DNA in the respiratory tract of rhesus monkeys: Pharmacolinetics, rat-to-monkey interspecies scaling, and extrapolation …

M Casanova, KT Morgan, WH Steinhagen… - … and applied toxicology, 1991 - Elsevier
… The results suggest that formaldehyde would generate lower concentrations of cross-links
in the nasal mucosa of humans than of monkeys, and much lower concentrations in humans …

Comparison of pulmonary/nasal CYP2F expression levels in rodents and rhesus macaque

RM Baldwin, WT Jewell, MV Fanucchi… - … of Pharmacology and …, 2004 - ASPET
… Comparison of stereoselectivity of naphthalene epoxidation in lung and nasal mucosa of
mouse, hamster, rat and rhesus monkey. J Pharmacol Exp Ther 261: 364-372. …

Comparative pathology of the nasal mucosa in laboratory animals exposed to inhaled irritants.

JR Harkema - Environmental Health Perspectives, 1990 - ehp.niehs.nih.gov
… that of the rhesus monkey is approximately 6200 mm2 (12). The human nasal cavity surface
area … The calculated surface area-to-volume ratio of the macaque monkey (775 mm2/cm3) is …

Leishmania (Viannia) braziliensis-induced chronic granulomatous cutaneous lesions affecting the nasal mucosa in the rhesus monkey (Macaca mulatta) model

A Teva, R Porrozzi, E Cupolillo, C Pirmez… - Parasitology, 2003 - cambridge.org
… We conclude that the rhesus monkey model could be useful for studying the interactions
between parasite and host determinants for infection, disease (virulence) and cure in L. (V.) …