… The final factor in support of targeting monocytes/macrophages for treatment of RA is the
differential activation of intracellular signal transduction pathways that underlie different …

… types, including monocytes, macrophages, and … monocyte/macrophage function. In this
review, we will discuss how the interplay between CD4 + T cells and monocytes/macrophages …

… by monocytes. In addition, we present unique profiles of monocytes/macrophages contributing
… We also outline novel approaches of tuning monocytes/macrophages by biologic drugs, …

… Monocytes and macrophages lie at the core of inflammation in RA due to their multifaceted
roles in disease pathogenesis [29]. They are potent cytokine producers with a clear activated …

… of monocytes, the antigenic expression on monocyte surface … monocytes subsets and
chemotaxis of circulating monocytes … monocytes as the circulating precursors of macrophages and …

… Both monocytes and synovial macrophages are key players in rheumatoid arthritis. These
cells are … Macrophages express adhesion molecules, chemokine receptors and other surface …

… bone erosion in arthritis. Their plasticity is … monocytes/macrophages and treat experimental
arthritis, as well as potential consequences of anti-TNF biotherapy on monocyte/macrophage …

… macrophages in RA have not been fully characterized, preliminary results in mouse models
of arthritis … of synovial macrophages, and to deciphering the properties of monocyte-derived …

… Potential and established approaches for modulation of monocyte/macrophage (Mφ)
functions in rheumatoid arthritis. COX-2, cyclooxygenase-2; EC, endothelial cells; FB, fibroblasts; …

… As one of the traditional therapeutic approaches used, gold salt has been shown to suppress
the infiltration of monocytes-macrophages to the synovium, which correlates with the down-…