[HTML][HTML] … plasma (PRP) induces chondroprotection via increasing autophagy, anti-inflammatory markers, and decreasing apoptosis in human osteoarthritic cartilage

M Moussa, D Lajeunesse, G Hilal, O El Atat… - Experimental cell …, 2017 - Elsevier
… However, its mechanism of action on improving cartilage repair remains to be … PRP on
osteoarthritic chondrocytes and to elucidate the mechanism by which PRP contributes to cartilage

[HTML][HTML] Basic science and clinical application of platelet-rich plasma for cartilage defects and osteoarthritis: a review

Y Zhu, M Yuan, HY Meng, AY Wang, QY Guo… - Osteoarthritis and …, 2013 - Elsevier
cartilage cells is currently being investigated to search for new therapies. Platelet-rich plasma
(PRP)… For culture of MSCs and cartilage cells, it might be substituted for fetal bovine serum (…

Biology of platelet-rich plasma and its clinical application in cartilage repair

X Xie, C Zhang, RS Tuan - Arthritis research & therapy, 2014 - Springer
… of a stable chondrocyte phenotype with PRP exposure. Similar effects were also noted in
human osteoarthritic chondrocytes [30]. The supernatant from platelet-rich fibrin (PRF) up-…

Platelet-rich plasma and cartilage repair

MI Kennedy, K Whitney, T Evans… - Current reviews in …, 2018 - Springer
… To improve the utilization of PRP for articular cartilage … inside osteoarthritic environments,
[2] the composition of PRP and … of PRP injections in the treatment of articular cartilage disease. …

Platelet-rich plasma in the pathologic processes of cartilage: review of basic science evidence

NA Smyth, CD Murawski, LA Fortier, BJ Cole… - … : The Journal of …, 2013 - Elsevier
… -rich plasma (PRP) in the treatment of pathologic processes of cartilage, both as an adjunct
to cartilage … strategy for osteoarthritis, with the intent of determining the effect of PRP and …

Comparison of platelet-rich plasma formulations for cartilage healing: an in vitro study

C Cavallo, G Filardo, E Mariani, E Kon, M Marcacci… - JBJS, 2014 - journals.lww.com
… L-PRP in the present study included increased secretion of hyaluronan by chondrocytes from
osteoarthritic human cartilage … would support use of L-PRP in the treatment of degenerative …

The role of platelet-rich plasma in cartilage pathology: an updated systematic review of the basic science evidence

MP Fice, JC Miller, R Christian, CP Hannon… - … : The Journal of …, 2019 - Elsevier
… To review the basic science studies on platelet-rich plasma (PRP) for cartilage and determine
… analysis regarding the mechanism of action and efficacy of PRP for cartilage pathology. …

PRP for degenerative cartilage disease: a systematic review of clinical studies

L Laver, N Marom, L Dnyanesh, O Mei-Dan… - Cartilage, 2017 - journals.sagepub.com
… To explore the utilization of platelet-rich plasma (PRP) for degenerative cartilage processes
and evaluate whether there is sufficient evidence to better define its potential effects. …

Platelet-rich plasma for articular cartilage repair

GD Abrams, RM Frank, LA Fortier… - Sports medicine and …, 2013 - journals.lww.com
… This article will focus on the use of PRP for articular cartilage repair. To serve as a … contained
within PRP as well as the catabolic enzymes and their signaling pathways, which PRP may …

Platelet-rich plasma increases anti-inflammatory markers in a human coculture model for osteoarthritis

C Osterman, MBR McCarthy, MP Cote… - … American journal of …, 2015 - journals.sagepub.com
… A coculture system was created using osteoarthritic cartilage and synovium from 9 patients
undergoing total knee arthroplasty. Interleukin-1β (IL-1β) was added to each coculture to …