… Nonetheless, we find here that this pathogen virulence activity elicits a RIPK1-dependent
apoptosis that functions as an effector-triggered immune response to promote control of …

… Human and murine CMVs apply different strategies in blocking RIPK3-dependent cell death.
This may reflect evolutionary variations in viral species to accommodate specificities of host …

… Since GSDME overexpression sensitizes apoptotic tumor cells to GSDME-dependent
pyroptosis (21), we next wondered whether GSDME expression correlates with susceptibility of …

… Consequently, pathogens, including viruses, target RIPK1 to … between RIPK1 and M45
resulted in blocking of RIPK1 … TRIF-induced apoptosis by blocking the RIPK1-TRIF interaction (…

… 8-dependent and caspase 3-mediated apoptosis. If caspase 8 activation is blocked by
pathogen effectors or genetic mutations, RIPK1 … Indeed, blocking RIPK1-induced cell death has …

… caspase-dependent pyroptosis and apoptosis or whether … activation of pyroptotic and apoptotic
markers, we observed … inactivation by microbial pathogens instigates robust inflammatory …

… are diverse, and often dependent on pathogen-specific virulence … This is partly due the fact
that RIPK1 and RIPK3 are implicated … discovery of novel virulence mechanisms of pathogens. …

… TAK1-deficient setting to mimic pathogen-induced priming and … unknown role for RIPK1
kinase activity–dependent and –… inflammasome, pyroptosis, apoptosis, and necroptosis, …

… that mimicking pS25 RIPK1 protected BMDMs from YopJ/P-dependent apoptosis following
Y… host cells by pathogenic Yersinia species. RIPK1 kinase-dependent apoptosis of the host …

… blockade of NF-κB and MAPK signaling. In this review, we discuss the regulation of apoptosis
in response to pathogen … infection, RIPK1 kinase-dependent apoptosis is essential for the …