[HTML][HTML] Anticancer drugs in the aquatic ecosystem: Environmental occurrence, ecotoxicological effect and risk assessment

D Li, H Chen, H Liu, D Schlenk, J Mu, S Lacorte… - Environment …, 2021 - Elsevier
… of major classes of anticancer drugs in water and sediments … , concentrations of most
anticancer drugs range from < 2 ng/L … are most sensitive to anticancer drugs. The most hazardous …

Prioritising anticancer drugs for environmental monitoring and risk assessment purposes

V Booker, C Halsall, N Llewellyn, A Johnson… - Science of the Total …, 2014 - Elsevier
… The aim of this study was to generate a shortlist of anticancer drugs (from the many drugs in
… can then be used to inform future screening programmes and/or targeted risk assessments. …

Environmental risk assessment of anti-cancer drugs and their transformation products: a focus on their genotoxicity characterization-state of knowledge and short …

AP Toolaram, K Kümmerer, M Schneider - Mutation Research/Reviews in …, 2014 - Elsevier
risk assessment is available for only a few anti-cancer drugsrisk assessment of anti-cancer
drugs, their metabolites and TPs in the environment. In fact, the presence of anti-cancer drugs

Environmental risk assessment of widely used anticancer drugs (5-fluorouracil, cisplatin, etoposide, imatinib mesylate)

M Mišík, M Filipic, A Nersesyan, M Kundi, M Isidori… - Water research, 2019 - Elsevier
Anticancer drugs are among the most toxic chemicals, which … This article describes the
results of risk assessments … and four widely used anticancer drugs with different mechanisms of …

Local environmental risk assessment of anticancer drugs in a developing country

RF da Silva, L de Lima Moura, LO Gavião… - … Risk Assessment: An …, 2020 - Taylor & Francis
… The consumption-based approach presented in this study is comprised of 20 anticancer
drugs between 2010 and 2017. The consumption was obtained from the hospital’s pharmacy …

[HTML][HTML] A simultaneous determination of anti-cancer drugs in hospital effluent by DLLME HPLC-FLD, together with a risk assessment

DM Souza, JF Reichert, AF Martins - Chemosphere, 2018 - Elsevier
… the risks attached to anti-cancer drugs in the Brazilian aquatic environment. Given this situation,
the present study seeks to determine the occurrence of anti-cancer drugs in … risks. Thus, …

The value of anticancer drugs—a regulatory view

F Pignatti, U Wilking, D Postmus, N Wilking… - Nature Reviews …, 2022 - nature.com
… In this Perspective, we discuss the different views, focusing on how regulators use benefit–risk
assessments in their approval decisions. While acknowledging that agreement on a …

[PDF][PDF] Environmental risk assessment of commonly used anti-cancer drugs

H Mıhçıokur - Cumhuriyet Science Journal, 2021 - dergipark.org.tr
risk assessment of anti-cancer drugs in the future. In the present study, the calculations
have been performed in order to assess the environmental risks of anti-cancer drugs as …

[HTML][HTML] Fate and effects of the residues of anticancer drugs in the environment

E Heath, M Filipič, T Kosjek, M Isidori - Environmental Science and …, 2016 - Springer
… an environmental risk assessment and recommend a case-by-case evaluation of the risk
knowledge and understanding of the risk posed by anticancer drug residues in the environment…

Anticancer drugs: Consumption trends in Spain, prediction of environmental concentrations and potential risks

H Franquet-Griell, C Gómez-Canela, F Ventura… - Environmental …, 2017 - Elsevier
… Estimation of risk After calculating PECs in surface water (PEC river ), risk assessment was
… The EMA guidelines recommends performing a risk assessment when PEC are higher than …