Carcinogenicity of acetaldehyde in alcoholic beverages: risk assessment outside ethanol metabolism
DW Lachenmeier, F Kanteres, J Rehm - Addiction, 2009 - Wiley Online Library
… ethanol metabolism poses a risk for drinkers of alcoholic beverages above … risk of ethanol
and metabolically formed acetaldehyde. The risk for acetaldehyde outside ethanol metabolism …
and metabolically formed acetaldehyde. The risk for acetaldehyde outside ethanol metabolism …
Ethanol metabolites: their role in the assessment of alcohol intake
FM Wurst, N Thon, M Yegles, A Schrück… - Alcoholism: Clinical …, 2015 - Wiley Online Library
… Depending on the biological material used for analysis, ethanol metabolites can be applied
in different settings such as assessment of alcohol intake, screening, prevention, diagnosis, …
in different settings such as assessment of alcohol intake, screening, prevention, diagnosis, …
An assessment of potential cancer risk following occupational exposure to ethanol
RJ Bevan, RJ Slack, P Holmes… - Journal of Toxicology and …, 2009 - Taylor & Francis
… is most likely due to its short half-life of evaporation (t½ = 11.7 s; CitationPendlington et al.,
2001), which, coupled with the possible metabolism of ethanol by skin cells (discussed more …
2001), which, coupled with the possible metabolism of ethanol by skin cells (discussed more …
[HTML][HTML] … , ethanol, acetaldehyde and noncarcinogenic higher alcohols, esters, and methanol compounds found in traditional alcoholic beverages. A risk assessment …
… Additionally, through risk assessment of noncarcinogenic compounds, we identified two …
metabolism is essential for yeast growth and cell division, producing compounds such as ethanol…
metabolism is essential for yeast growth and cell division, producing compounds such as ethanol…
[HTML][HTML] Alcohol metabolism and cancer risk
HK Seitz, P Becker - Alcohol Research & Health, 2007 - ncbi.nlm.nih.gov
… is generated during ethanol metabolism, when the ethanol is … carbohydrates to acetaldehyde
and ethanol. Although the … produce small amounts of ethanol and acetaldehyde. More …
and ethanol. Although the … produce small amounts of ethanol and acetaldehyde. More …
[HTML][HTML] Short-term salivary acetaldehyde increase due to direct exposure to alcoholic beverages as an additional cancer risk factor beyond ethanol metabolism
DW Lachenmeier, YB Monakhova - Journal of experimental & clinical …, 2011 - Springer
… focused on salivary acetaldehyde that is formed either from ethanol metabolism in the epithelia
or from microbial oxidation of ethanol by the oral microflora. This study was conducted to …
or from microbial oxidation of ethanol by the oral microflora. This study was conducted to …
[HTML][HTML] Ethanol metabolism and melanoma
Z Zhai, T Yamauchi, S Shangraw, V Hou, A Matsumoto… - Cancers, 2023 - mdpi.com
… Humans are unavoidably exposed to ethanol and AcAH daily in multiple ways, … ethanol
and AcAH in the skin, their metabolic pathways, and the consequences of dysfunctional ethanol …
and AcAH in the skin, their metabolic pathways, and the consequences of dysfunctional ethanol …
Computational models of ethanol‐induced neurodevelopmental toxicity across species: Implications for risk assessment
JM Gohlke, WC Griffith… - Birth Defects Research …, 2008 - Wiley Online Library
… low-dose ethanol exposure (Fig. 4), enabling us to evaluate our model's utility in risk
assessment. Although animal studies have been used extensively to determine ethanol-induced …
assessment. Although animal studies have been used extensively to determine ethanol-induced …
[HTML][HTML] Acetaldehyde as an underestimated risk factor for cancer development: role of genetics in ethanol metabolism
HK Seitz, F Stickel - Genes & nutrition, 2010 - Springer
… methyl transfer and abnormal metabolism of vitamin A and its … AA, the first metabolite of
ethanol oxidation, is carcinogenic [4, … metabolic steps are modulated by the activity of the ethanol …
ethanol oxidation, is carcinogenic [4, … metabolic steps are modulated by the activity of the ethanol …
Epidemiology-based risk assessment using the benchmark dose/margin of exposure approach: the example of ethanol and liver cirrhosis
DW Lachenmeier, F Kanteres… - International Journal of …, 2011 - academic.oup.com
… For acetaldehyde directly contained in the beverages (ie outside ethanol metabolism),
we had previously calculated an average MOE of 498. For ethyl carbamate, the MOE was ∼5000. …
we had previously calculated an average MOE of 498. For ethyl carbamate, the MOE was ∼5000. …
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