Psoriasis and cardiovascular disease risk in European and East Asian populations: evidence from meta-analysis and Mendelian randomization analysis
L Zhang, Y Wang, L Qiu, J Wu - BMC medicine, 2022 - Springer
… for cardiovascular risk factors. With MR, we systematically evaluated the causality between
psoriasis and CAD, MI, and HF risk and found that psoriasis was linked with a higher risk of …
psoriasis and CAD, MI, and HF risk and found that psoriasis was linked with a higher risk of …
The association between psoriasis and risk of cardiovascular disease: A mendelian randomization analysis
N Gao, M Kong, X Li, X Zhu, D Wei, M Ni… - Frontiers in …, 2022 - frontiersin.org
… A meta-analysis of 33 observational studies showed that patients with psoriasis had a higher
risk of MI… Another meta-analysis of 13 studies showed an increase in overall cardiovascular …
risk of MI… Another meta-analysis of 13 studies showed an increase in overall cardiovascular …
[HTML][HTML] Serum lipids and risk of incident psoriasis: a prospective cohort study from the UK biobank study and mendelian randomization analysis
… Our subsequent Mendelian randomization analysis reinforced the main finding … psoriasis
genetically. In conclusion, serum high-density lipoprotein/triglyceride levels predict psoriasis, …
genetically. In conclusion, serum high-density lipoprotein/triglyceride levels predict psoriasis, …
Association of lipid-lowering drugs with risk of psoriasis: a mendelian randomization study
… Although the results of the current analysis only provide inference for psoriasis prevention,
the aforementioned animal models support PCSK9 as a potential target for treatment. Clinical …
the aforementioned animal models support PCSK9 as a potential target for treatment. Clinical …
The relationship between blood lipid and risk of psoriasis: univariable and multivariable Mendelian randomization analysis
… multivariable Mendelian randomization (MVMR). Finally, we performed a reversal MR
analysis to explore the effect of psoriasis on blood lipid. This reversal causation analysis will help …
analysis to explore the effect of psoriasis on blood lipid. This reversal causation analysis will help …
Impact of biologic therapies on risk of major adverse cardiovascular events in patients with psoriasis: systematic review and meta‐analysis of randomized controlled …
… psoriasis. We aimed to examine the risk of MACEs in adult patients with plaque psoriasis
that are exposed to biologic therapies via a meta‐analysis of randomized controlled trials (…
that are exposed to biologic therapies via a meta‐analysis of randomized controlled trials (…
Efficacy and safety of systemic treatments for moderate‐to‐severe psoriasis: meta‐analysis of randomized controlled trials
J Schmitt, S Rosumeck… - British Journal of …, 2014 - academic.oup.com
… of participants with 75% improvement in Psoriasis Area and Severity Index at … ‐analysis of
risk differences (RDs). In total, 48 eligible RCTs totalling 16 696 patients (11 178 randomized …
risk differences (RDs). In total, 48 eligible RCTs totalling 16 696 patients (11 178 randomized …
Evidence of a causal relationship between body mass index and psoriasis: A mendelian randomization study
A Budu-Aggrey, B Brumpton, J Tyrrell, S Watkins… - PLoS …, 2019 - journals.plos.org
… published BMI and psoriasis genome-wide … analysis with genetic instruments comprising
variants from recent genome-wide analyses for psoriasis were used to test whether genetic risk …
variants from recent genome-wide analyses for psoriasis were used to test whether genetic risk …
Elevated plasma triglycerides increase the risk of psoriasis: a cohort and Mendelian randomization study
AM Greve, AB Wulff, SE Bojesen… - British Journal of …, 2024 - academic.oup.com
… analyses (Mendelian randomization) to study the hypothesis that elevated plasma triglycerides
confer increased risk of developing psoriasis … an increased risk of later psoriasis in both …
confer increased risk of developing psoriasis … an increased risk of later psoriasis in both …
Mendelian randomization analysis of psoriasis and psoriatic arthritis associated with risks of ulcerative colitis
J Pan, Y Lv, L Wang, X Chang… - Skin Research and …, 2024 - Wiley Online Library
… This study found that psoriasis and PsA significantly increased the risk of UC, and conversely,
UC also significantly increased the risk of psoriasis and PsA. In this regard, these results …
UC also significantly increased the risk of psoriasis and PsA. In this regard, these results …
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