Sex differences in DNA methylation may contribute to risk of PTSD and depression: a review of existing evidence
… least some of the heightened risk of PTSD onset in women (hypothesis (… risk for PTSD
following trauma,21 and this twofold increased risk of PTSD persists across a wide range of trauma …
following trauma,21 and this twofold increased risk of PTSD persists across a wide range of trauma …
[HTML][HTML] The effects of trauma, with or without PTSD, on the transgenerational DNA methylation alterations in human offsprings
… While knowledge of possible epigenetic underpinnings of the association between
exposure to trauma and risk of PTSD has been discussed in several reviews, it remains to be …
exposure to trauma and risk of PTSD has been discussed in several reviews, it remains to be …
Adverse childhood experience, genes, and PTSD risk in soldiers: a methylation study
MR Hossack, MW Reid, JK Aden, T Gibbons… - Military …, 2020 - academic.oup.com
… DNA methylation patterns of multiple genes have been studied in both civilian populations
and military personnel with post-traumatic stress disorder (PTSD)… that the methylation levels of …
and military personnel with post-traumatic stress disorder (PTSD)… that the methylation levels of …
DNA methylation correlates of PTSD: Recent findings and technical challenges
… -dependent regulation of FKBP5 was associated with increased risk for adulthood stress-…
be selectively demethylated in risk allele carriers with childhood but not adult trauma. In in vitro …
be selectively demethylated in risk allele carriers with childhood but not adult trauma. In in vitro …
[HTML][HTML] Blood-based DNA methylation and exposure risk scores predict PTSD with high accuracy in military and civilian cohorts
… risk for complex disorders such as PTSD. Our goal was to develop and validate Methylation
Risk Scores (MRS) using machine learning to distinguish individuals who have PTSD from …
Risk Scores (MRS) using machine learning to distinguish individuals who have PTSD from …
DNA methylation signatures of childhood trauma predict psychiatric disorders and other adverse outcomes 17 years after exposure
CLJD van den Oord, WE Copeland, M Zhao… - Molecular …, 2022 - nature.com
… childhood trauma and DNA methylation [4]. Almost all studies link methylation changes in …
As cumulative trauma exposure seems a critical determinant of health risks [7], we summed …
As cumulative trauma exposure seems a critical determinant of health risks [7], we summed …
[HTML][HTML] An epigenome-wide DNA methylation study of PTSD and depression in World Trade Center responders
… of PTSD and of MDD to date, investigating DNA methylation … We found no significant
genome-wide methylation differences … events on risk for posttraumatic stress disorder. Depress …
genome-wide methylation differences … events on risk for posttraumatic stress disorder. Depress …
Epigenome-wide meta-analysis of PTSD symptom severity in three military cohorts implicates DNA methylation changes in genes involved in immune system and …
… is therefore a crucial step in deciphering mechanisms of risk and resilience. In this … PTSD
symptom severity (PTSS) and changes in PTSS over time, using whole blood DNA methylation (…
symptom severity (PTSS) and changes in PTSS over time, using whole blood DNA methylation (…
PTSD is associated with increased DNA methylation across regions of HLA-DPB1 and SPATC1L
… Here we aimed to identify epigenetic differences associated with PTSD. DNA methylation
data … This study supports an emerging literature linking PTSD risk to genetic and epigenetic …
data … This study supports an emerging literature linking PTSD risk to genetic and epigenetic …
Accelerated DNA methylation age: associations with PTSD and neural integrity
… Posttraumatic stress disorder (PTSD) has been identified as a chronic stress-related
condition that may accelerate cellular aging, increasing risk for neuronal cell death via oxidative …
condition that may accelerate cellular aging, increasing risk for neuronal cell death via oxidative …
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