… of IgM-OCB in both study groups. In addition, we did not find any association between
increased IgM-Index values and the frequency of relapses or a shorter time span for a relapse. In …

… a role for IgM antibodies in MS, such as the correlation of “de novo” intrathecal C3 synthesis
and IgM synthesis in MS.6 In addition, a correlation between local IgM synthesis and myelin …

… association between ITMS and the risk of future relapses nor disease progression. Reproduction
in independent or multicentric studies is therefore warranted to confirm these findings. …

… Reibergram nor IgM index >0.1 identified patients experiencing a subsequent relapse. …
-OCMB were significantly associated with a higher risk of a second relapse at a shorter time (aHR …

… reported that intrathecal synthesis is not associated with an increased risk of a relapse after
a … in children with MS correlates with a lower relapse rate in the first two years. We also show …

… IgM synthesis (presence of IgM-OCB in the CSF) does not correlate with the risk of relapse in
… demonstrated that intrathecal IgM synthesis is not a negative prognostic marker of disease …

… synthesis compared with IgM and IgA synthesis in patients with MS. Associations of other
CSF parameters on disability worsening and relapse … of intrathecal IgG synthesis with risk of …

… Intrathecal IgM synthesis did not affect the risk of a second relapse or evidence of MRI activity
in … Status Scale and progression index in patients with or without intrathecal IgM synthesis. …

… and relapses, significantly lower serum IgM levels were … levels is the balance between
synthetic and catabolic rate of … was not associated with an increased risk for infections in a …

… IgM synthesis predicts future relapse activity and is persistent within the CSF, it is reasonable
to believe that the proportion of IgM … are a risk factor for a second clinical relapse (HR = 2.2)…