Cardiovascular precision medicine in the genomics era

AM Dainis, EA Ashley - JACC: Basic to Translational Science, 2018 - jacc.org
… The MI-GENES (Myocardial Infarction Genes) Study researched whether informing patients
of their genomic risk score (GRS) in addition to a conventional risk score (CRS) would affect …

[HTML][HTML] The clinical practice of risk reduction for Alzheimer's disease: a precision medicine approach

RS Isaacson, CA Ganzer, H Hristov, K Hackett… - Alzheimer's & …, 2018 - Elsevier
… AD risk reduction through an evidence-based, multidomain precision medicine approach.
We … of personalized risk management within an international network of clinician researchers. …

Challenges in IBD research: precision medicine

LA Denson, M Curran, DPB McGovern… - Inflammatory bowel …, 2019 - academic.oup.com
… In order to provide precision medicine to patients with IBD, we need to be able to better
define patient subsets at different levels risk of developing aggressive disease course and who …

Polygenic risk scores for cardiometabolic traits demonstrate importance of ancestry for predictive precision medicine

RL Kember, SS Verma, A Verma, B Xiao… - PACIFIC …, 2023 - World Scientific
… The ultimate success of PRS in precision medicinerisk profile for each patient. By addressing
these key aspects and enhancing our understanding of PRSs role in precision medicine, …

American Joint Committee on Cancer acceptance criteria for inclusion of risk models for individualized prognosis in the practice of precision medicine

…, AJCC Precision Medicine Core - CA: a cancer journal …, 2016 - Wiley Online Library
… The AJCC has increasingly recognized the growing need for more accurate and probabilistic
individualized outcome prediction for precision medicine that would incorporate additional …

The future of precision medicine: towards a more predictive personalized medicine

O Elemento - Emerging topics in life sciences, 2020 - portlandpress.com
… of precision medicine and highlight current research that may soon make precision medicine
more … Novel tools such as polygenic risk scores that combine multiple genetic variants are …

Phenotypic subtypes of OSA: a challenge and opportunity for precision medicine

A Zinchuk, HK Yaggi - Chest, 2020 - Elsevier
… , reflected by varying risk factors, pathophysiological causes, … , or both, exhibit varying risks
of cardiovascular disease and … ) of phenotypic subtypes in precision medicine for OSA. It also …

From GWAS to functional genomics-based precision medicine

DL Mattson, M Liang - Nature Reviews Nephrology, 2017 - nature.com
… of a genetic risk score and its application to an independent group of individuals demonstrates
the potential application of identified genetic loci for use in a precision medicine approach …

Challenges and future prospects of precision medicine in psychiatry

M Manchia, C Pisanu, A Squassina… - … personalized medicine, 2020 - Taylor & Francis
… The application of precision medicine in … of the risk and outcome prediction in schizophrenia.
In this narrative review, we summarized the most important findings in precision medicine in …

Equity and value in 'precision medicine'

M Gray, T Lagerberg, V Dombrádi - The New Bioethics, 2017 - Taylor & Francis
risk estimations (CitationHunter 2016). This potential lack of clarity on risk despite the use of
precision medicine … Doctors need to understand the implications of these scores if they are to …