Polygenic risk scores: from research tools to clinical instruments

CM Lewis, E Vassos - Genome medicine, 2020 - Springer
risk is most often assessed through the polygenic risk score (PRS), a weighted sum of the
number of risk … In this review, we consider how polygenic risk scores may be informative at …

Systematic review and meta-analysis of the performance of clinical risk assessment instruments for screening for osteoporosis or low bone density

S Nayak, DL Edwards, AA Saleh… - Osteoporosis …, 2015 - Springer
… that assessed instruments for predicting absolute fracture risk. … -analysis of clinical risk
assessment instruments for identifying … of risk instruments for predicting absolute fracture risk were …

Predicting suicidal behaviours using clinical instruments: systematic review and meta-analysis of positive predictive values for risk scales

G Carter, A Milner, K McGill, J Pirkis… - The British Journal of …, 2017 - cambridge.org
… Many clinical instruments have been utilised for prediction including: psychological scales
such as versions of the Beck Depression Inventory (BDI)4 or the SADPERSONS scale;5 …

Risk assessment instruments in clinical practice

G Côté, AG Crocker, TL Nicholls… - The Canadian Journal …, 2012 - journals.sagepub.com
… To determine whether the items in one of the most widely validated instruments of violence
risk assessment, the Historical-Clinical-Risk Management-20 (HCR-20), are used in review …

Is it worth the risk? A systematic review of instruments that measure risk propensity for use in the health setting

JD Harrison, JM Young, P Butow, G Salkeld… - Social science & …, 2005 - Elsevier
instruments that could be used to elicit a patients overall risk propensity in a clinical setting.
… and perspectives on risk have been generated, an individual's risk propensity remains a …

Prognostic accuracy and clinical utility of psychometric instruments for individuals at clinical high-risk of psychosis: a systematic review and meta-analysis

D Oliver, M Arribas, J Radua, G Salazar de Pablo… - Molecular …, 2022 - nature.com
… in CHR-P psychometric instruments, with Se being 0.36 higher … Risk Score for diabetes
[63]. There is, therefore, a clear need to focus efforts on improving the ability of these instruments

A review of suicide risk assessment instruments and approaches

M Lotito, E Cook - Mental Health Clinician, 2015 - meridian.allenpress.com
… about an individual's suicide risk through the clinical interview. As such, clinicians should
avoid using the obtained cutoff score as an indicator of a patient's risk of suicide. Instead, …

Performance of risk assessment instruments for predicting osteoporotic fracture risk: a systematic review

S Nayak, DL Edwards, AA Saleh… - Osteoporosis …, 2014 - Springer
… estimates of absolute fracture risk match observed fracture incidence in … clinical fracture risk
assessment instruments to assess their performance in estimating absolute fracture risk over …

Beyond bone mineral density: can existing clinical risk assessment instruments identify women at increased risk of osteoporosis?

LE Wehren, ES Siris - Journal of internal medicine, 2004 - Wiley Online Library
… the performance of these instruments to identify those most … of screening instruments
comprised osteoporosis clinical risk … the performance of several risk factor screening instruments. …

Performance and agreement of risk stratification instruments for postoperative delirium in persons aged 50 years or older

CJ Jansen, AR Absalom, GH de Bock… - PloS one, 2014 - journals.plos.org
risk stratification instruments for postoperative delirium was poor. Although some caution
is needed because the risk stratification instruments … in clinical practice can be questioned. …