… We did a combined analysis of individual-participant data from three large-scale data sources
in 19 high-income countries (the Emerging Risk Factors Collaboration, EPIC-CVD, and the …

… risk stratification. Third, we emphasize that there is usually no universally optimal threshold
but rather that a plausible risk threshold … results for multiple risk thresholds when developing …

… In the 2-stage screening scenario, a diabetes risk threshold of ≥ 5% risk in combination with
impaired fasting glucose resulted in 20% of US adults identified for intervention when using …

This paper describes a framework for the risk assessment of combined exposure to multiple
chemicals based on and developed subsequent to the World Health Organization/…

… In risk assessment, thresholds are generally believed to exist … for a single agent, the threshold
is represented by a single dose … This article describes threshold models for combination …

… , defining it as amplification flood risk. In addition, the categorization of amplification flood
risk and the determination of distinct risk thresholds (ie, the combined rainfall and river level …

… -level threshold analysis) or by changing the combined evidence … We suggest that threshold
analysis be integrated into the … analysis, the included studies should be assessed for risk of …

… using multivariate competing risks regression models with censoring at April 2011 (latest
date for linkage to national data sets) with death included as a competing risk. For individuals …

… In such cases, it can be very difficult to assess whether a particular combination of risks …
threshold. Thus, SMART provides a more accurate portrayal of risk acceptance when either risk …

… A substantial challenge lies in the assessment of combination effects from large numbers
of … good evidence for combination effects at levels around experimental thresholds. One …