Prostate cancer (PCa) risk variants and risk of fatal PCa in the national cancer institute breast and prostate cancer cohort consortium
IM Shui, S Lindström, AS Kibel, SI Berndt, D Campa… - European urology, 2014 - Elsevier
… In this report, we assessed whether established PCa risk variants could predict PCSM. We
found eight risk variants associated with PCSM: One predicted an increased risk of PCSM, …
found eight risk variants associated with PCSM: One predicted an increased risk of PCSM, …
Association of prostate cancer risk variants with gene expression in normal and tumor tissue
… genetic variants are associated with prostate cancer risk, … variants influence gene expression
in prostate tissue. We therefore examined the association of prostate cancer risk variants …
in prostate tissue. We therefore examined the association of prostate cancer risk variants …
Association of prostate cancer risk variants with clinicopathologic characteristics of the disease
J Xu, SD Isaacs, J Sun, G Li, KE Wiley, Y Zhu… - Clinical Cancer …, 2008 - AACR
… variants with clinicopathologic variables of prostate cancer, we systematical evaluated all
prostate cancer risk variants … prostatectomy for treatment of prostate cancer at Johns Hopkins …
prostate cancer risk variants … prostatectomy for treatment of prostate cancer at Johns Hopkins …
A large multiethnic genome-wide association study of prostate cancer identifies novel risk variants and substantial ethnic differences
TJ Hoffmann, SK Van Den Eeden, LC Sakoda… - Cancer discovery, 2015 - AACR
… new risk variants for prostate cancer, confirm many previously reported associations at
various levels across ethnic groups, and provide independent evidence that additional risk SNPs …
various levels across ethnic groups, and provide independent evidence that additional risk SNPs …
Genetic variants associated with predisposition to prostate cancer and potential clinical implications
CL Goh, FR Schumacher, D Easton… - Journal of internal …, 2012 - Wiley Online Library
… Several studies have explored the capacity of established prostate cancer risk variants to
differentiate between the less aggressive and more aggressive disease. Somatic genetic …
differentiate between the less aggressive and more aggressive disease. Somatic genetic …
Combined effect of a polygenic risk score and rare genetic variants on prostate cancer risk
… UK Biobank, including 3568 prostate cancer cases, to examine … variants and common
prostate cancer risk variants, measured using a polygenic risk score (PRS), on prostate cancer risk…
prostate cancer risk variants, measured using a polygenic risk score (PRS), on prostate cancer risk…
[HTML][HTML] Germline genetics of prostate cancer: prevalence of risk variants and clinical implications for disease management
DK Doan, KT Schmidt, CH Chau, WD Figg - Cancers, 2021 - mdpi.com
… of the molecular basis of prostate cancer have resulted in the … variants that places them at
increased risk of developing the disease. The goal of precision oncology in prostate cancer is …
increased risk of developing the disease. The goal of precision oncology in prostate cancer is …
[PDF][PDF] Five genetic variants associated with prostate cancer
… With 10 additional risk variants reported since February 2008, it is expected that the sensitivity
and specificity will be further improved. We do not advocate replacing the PSA test with …
and specificity will be further improved. We do not advocate replacing the PSA test with …
Sequence variants at 22q13 are associated with prostate cancer risk
J Sun, SL Zheng, F Wiklund, SD Isaacs, G Li, KE Wiley… - Cancer research, 2009 - AACR
… The goal of this study is to search for these risk variants using existing data from two GWAS:
… risk variants that are associated with more clinically relevant, aggressive prostate cancer, we …
… risk variants that are associated with more clinically relevant, aggressive prostate cancer, we …
Individual and cumulative effect of prostate cancer risk‐associated variants on clinicopathologic variables in 5,895 prostate cancer patients
AK Kader, J Sun, SD Isaacs, KE Wiley, G Yan… - … Prostate, 2009 - Wiley Online Library
… (SNPs) have been associated with prostate cancer (PCa) risk from genome-wide association
… Two variants on chromosome 17 confer prostate cancer risk, and the one in TCF2 protects …
… Two variants on chromosome 17 confer prostate cancer risk, and the one in TCF2 protects …
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