[PDF][PDF] BIOAVAILABILITY ENHANCEMENT STRATEGIES FOR RIVAROXABAN: A NOTEWORTHY REVIEW

AA AL-SHOUBKI, MH TEAIMA, R ABDELMONEM… - Int J App …, 2023 - researchgate.net
… formulation and Xarelto® … Xarelto® in fed state. Hence, the researchers concluded that
the SNEDDS formulation developed in this study is useful in enhancing the oral bioavailability

Enhanced oral bioavailability of Rivaroxaban-Loaded microspheres by optimizing the polymer and surfactant based on molecular interaction mechanisms

MJ Choi, MR Woo, K Baek, JH Park… - Molecular …, 2023 - ACS Publications
… Moreover, the oral bioavailability of RXB was improved by 2.4… the highest improvement in
oral bioavailability compared to … , dissolution rate, and bioavailability of RXB, suggesting that …

[HTML][HTML] Potential application of sucrose acetate isobutyrate, and glyceryl monooleate for nanonization and bioavailability enhancement of rivaroxaban tablets

AA Al-Shoubki, MH Teaima, R Abdelmonem… - Pharmaceutical Science …, 2024 - Elsevier
… SAIB and GMO is critical to enhancing the dissolution and bioavailability of RXB in nano …
has revolutionized drug delivery by enhancing drug solubility, bioavailability, and efficacy, …

Preparation and optimization of rivaroxaban by self-nanoemulsifying drug delivery system (SNEDDS) for enhanced oral bioavailability and no food effect

X Xue, M Cao, L Ren, Y Qian, G Chen - Aaps Pharmscitech, 2018 - Springer
Xarelto® were carried out in adult beagle dog, rivaroxaban with no food effect was achieved
in SNEDDS formulation compared with Xarelto… increase the oral bioavailability and diminish …

Sustained release and enhanced oral bioavailability of rivaroxaban by PLGA nanoparticles with no food effect

MK Anwer, M Mohammad, M Iqbal, MN Ansari… - Journal of thrombosis …, 2020 - Springer
… An improved formulation of rivaroxaban with enhanced bioavailability with no effect was …
the rivaroxaban were designed by using central composite design. The optimized rivaroxaban

Quality-by-design-based development of Rivaroxaban-Loaded Liquisolid Compact tablets with Improved Biopharmaceutical attributes

P Shah, H Desai, B Vyas, M Lalan, M Kulkarni - AAPS PharmSciTech, 2023 - Springer
… and Xarelto® tablets respectively, demonstrating that developed formulation had a greater
oral bioavailability. … enhancement in bioavailability of poorly soluble actives. The first effective …

Novel rivaroxaban-loaded microsphere systems with different surface microstructure for enhanced oral bioavailability

MJ Choi, MR Woo, K Baek, JS Kim, JO Kim… - Drug Delivery and …, 2024 - Springer
… and in research because of its excellent solubility-enhancing effect [19]. These chemicals
were used to enhance the oral bioavailability of rivaroxaban, a poorly soluble drug, by forming …

On absorption modeling and food effect prediction of rivaroxaban, a BCS II drug orally administered as an immediate-release tablet

V Kushwah, S Arora, M Tamás Katona, D Modhave… - Pharmaceutics, 2021 - mdpi.com
… The bioavailability of Riva upon oral administration of Xarelto IR … in bioavailability of Xarelto
during the fed state simulation was found, which could be due to the enhanced dissolution of …

Amalgamation of solid dispersion and melt adsorption techniques for augmentation of oral bioavailability of novel anticoagulant rivaroxaban

PJ Shah, MP Patel, J Shah, AB Nair, S Kotta… - Drug Delivery and …, 2022 - Springer
… in bioavailability of RXN from SDAs when compared to its suspension and marketed
formulation, confirming an increase in solubility and dissolution rate thus enhancing the oral

Rivaroxaban eutectics with improved solubility, dissolution rates, bioavailability and stability

PS Shaligram, CP George, H Sharma, KR Mahadik… - …, 2023 - pubs.rsc.org
enhancement in the solubility of RXB. The powder dissolution rate of the eutectics showed
considerable enhancement … 1.5 and 1.4 times enhancement in relative bioavailability for RXB–…