Efficacy and safety of direct oral anticoagulants in obese patients with venous thromboembolism

RA Sa, F Al-Ani, A Lazo-Langner, ML Louzada - Blood, 2019 - Elsevier
… inclusion criteria: 278 (35.8%) obese patients treated with DOACs, 266 (34.2%) non-obese
patients as defined herein. However, since most of our patients were treated with rivaroxaban

Effect of body weight on efficacy and safety of direct oral anticoagulants in the treatment of patients with acute venous thromboembolism: a meta-analysis of …

MND Di Minno, R Lupoli, A Di Minno… - Annals of …, 2015 - Taylor & Francis
… weighing 50 kg, 70–80 kg, or > 120 kg were given a single 10 mg dose of rivaroxaban. In …
achieve a therapeutic International Normalized Ratios (INR) compared to non-obese patients (…

[HTML][HTML] The Effectiveness and Safety of Direct Oral Anticoagulants in Obese Patients With Atrial Fibrillation: A Network Meta-Analysis

QM Salah, S Bhandari, A Chand, S Khan, SHA Tirmzi… - Cureus, 2023 - ncbi.nlm.nih.gov
… We used network meta-analysis as it allows for the simultaneous comparison of multiple
treatments (apixaban, dabigatran, rivaroxaban, and warfarin) within the same analysis. This …

Thromboembolic and bleeding risk in obese patients with atrial fibrillation according to different anticoagulation strategies

G Patti, L Pecen, MC Manu, K Huber, M Rohla… - International Journal of …, 2020 - Elsevier
… in these patients; as a consequence, the issue of whether the newer … therapies in obese
patients provide a protection from thromboembolic events similar to non-obese patients

Efficacy and Safety of Direct Oral Anticoagulants versus Warfarin in Obese Patients (BMI≥ 30 kg/m2) with Atrial Fibrillation or Venous Thromboembolism: An Updated …

P Karakasis, N Ktenopoulos, K Pamporis… - Journal of Clinical …, 2024 - mdpi.com
… the use of DOACs in non-obese patients with cancer-related … oral anticoagulants in patients
with obesity for treatment and … versus non-obese patients receiving rivaroxaban therapy: An …

Direct oral anticoagulants in the treatment of venous thromboembolism: Use in patients with advanced renal impairment, obesity, or other weight-related special …

PP Dobesh, MM Kernan… - Seminars in Respiratory …, 2021 - thieme-connect.com
… [51] All patients in this study received the appropriate rivaroxaban dose of 15 mg daily. In …
in patients receiving VTE treatment with rivaroxaban 20 mg daily.[78] There were 105 patients

Comparing direct oral anticoagulants and vitamin K antagonist use in morbidly obese patients with venous thromboembolism: a single center retrospective cohort …

LC Scott, J Li, LA Cafuir, M Gaddh, CL Kempton - EJHaem, 2022 - Wiley Online Library
… /m 2 ) patients who were more likely than non-obese patients to be … patients with VTE
receiving rivaroxaban had similar risks of recurrent VTE and major bleeding compared with patients

Anticoagulation at the extremes of body weight: choices and dosing

GJB McCaughan, EJ Favaloro, L Pasalic… - Expert review of …, 2018 - Taylor & Francis
… In a study of otherwise healthy obese and non-obese individuals administered enoxaparin
1.5 … In the dose finding study of rivaroxaban, it was noted that rivaroxaban concentrations did …

[HTML][HTML] Annals of Cardiology and Vascular Medicine

G Stern - meddocsonline.org
… with apixaban and rivaroxaban treatment in morbidly obese versus non-obese patients
In this analysis of 291 patients, apixaban and rivaroxaban were not associated with an …

Relationship between body mass index and outcomes in patients with atrial fibrillation treated with edoxaban or warfarin in the ENGAGE AF-TIMI 48 trial

G Boriani, CT Ruff, JF Kuder, M Shi… - European heart …, 2019 - academic.oup.com
… obese patients than in non-obese patients, 1 but, in a retrospective analysis of the patients
… In both studies no differences in the relative effects of NOACs (rivaroxaban and apixaban, …