In-silico selection of aptamer: A review on the revolutionary approach to understand the aptamer design and interaction through computational chemistry
… the computational time spent through RNA aptamers selection approach … aptamer screening,
Rabal O., and co-workers[17] proposed a workflow starting from the designing of aptamers …
Rabal O., and co-workers[17] proposed a workflow starting from the designing of aptamers …
In silico approaches to RNA aptamer design
M Hamada - Biochimie, 2018 - Elsevier
… select candidate RNA aptamers that bind to a target protein with high affinity and specificity.
After candidate selection, … Specifically, several types of computational methods are described …
After candidate selection, … Specifically, several types of computational methods are described …
Computational tools for aptamer identification and optimization
D Sun, M Sun, J Zhang, X Lin, Y Zhang, F Lin… - TrAC Trends in …, 2022 - Elsevier
… tools at work, we also review recent advanced studies on in silico selection of aptamers
against SARS-CoV-2. This review will aid in the development and use of high-throughput, less …
against SARS-CoV-2. This review will aid in the development and use of high-throughput, less …
In silico selection of RNA aptamers
Y Chushak, MO Stone - Nucleic acids research, 2009 - academic.oup.com
… computational approach for designing a starting pool of RNA sequences for the selection of
RNA aptamers … Our approach consists of three steps: (i) selection of RNA sequences based …
RNA aptamers … Our approach consists of three steps: (i) selection of RNA sequences based …
Computational design of RNA libraries for in vitro selection of aptamers
YG Chushak, JA Martin, JL Chávez… - … : Methods and Protocols, 2014 - Springer
… a random library of RNA sequences, and many aptamers selected from such random
pools … We present here a computational approach for designing a starting library of RNA …
pools … We present here a computational approach for designing a starting library of RNA …
Computational approaches toward the design of pools for the in vitro selection of complex aptamers
… in RNA/DNA pools, and Genetic Filtering designs RNA/DNA pools to a specified structure
distribution, whether uniform or otherwise. We show that using our computationally … to select for …
distribution, whether uniform or otherwise. We show that using our computationally … to select for …
AptCompare: optimized de novo motif discovery of RNA aptamers via HTS-SELEX
KR Shieh, C Kratschmer, KE Maier, JM Greally… - …, 2020 - academic.oup.com
… of RNA aptamer motifs and uses a simple weighted ranking to order the candidate aptamers,
… the top-ranked candidate aptamers from a previously published selection experiment in our …
… the top-ranked candidate aptamers from a previously published selection experiment in our …
Computational predictive approaches for interaction and structure of aptamers
… for effective aptamer selection and designing … computational predictive approaches of the
aptamer has been organized. Generally, the computational prediction approaches of aptamer …
aptamer has been organized. Generally, the computational prediction approaches of aptamer …
Computational Selection of RNA Aptamer against Angiopoietin‐2 and Experimental Evaluation
… -protein interactions by using the ZDOCK scoring function is that the RNA aptamers used in
… RNA aptamer sequences were generated from three reference structures of aptamers, and …
… RNA aptamer sequences were generated from three reference structures of aptamers, and …
Structural computational modeling of RNA aptamers
… of long RNA sequences and the slow post-selection … In a recent study we used computational
RNA structural and RNA/… membrane antigen (PSMA) RNA aptamer (70 nucleotides long) […
RNA structural and RNA/… membrane antigen (PSMA) RNA aptamer (70 nucleotides long) […
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