… evaluating the feasibility and rationality of using ZDOCK and ZRANK algorithms, we took the
16 RNA aptamers … , which were consistent with the experimental results in the literatures (…

… In this section, we review several scores for ranking RNA aptamers obtained from (HT-)SELEX
experiments, in which utilizing all the information from HT-SELEX reads is important. …

… In these experiments, aptamers were shown to be suitable for cell conditions and the
major concern was how to regulate and detect them inside the cell. Finally, after 13 years, …

… EXperimental enrichment), are important candidates for therapeutic and diagnostic applications.
RNA aptamers … In this review, we describe methods for generating RNA aptamers (the …

… evaluating the performances of in silico HT-SELEX analysis methods. Here we present RNA
aptamer … silico method for identifying high binding-affinity aptamers from HT-SELEX data by …

… of the constant regions in case RNA aptamers shall be selected. … DNA aptamers or is first in
vitro transcribed to RNA using T7-RNA … In vivo experiments confirmed the aptamer activity in …

… As more labs have started to carry out aptamer selection experiments, and more and more
… immobilized by chelators for aptamer selection [81,82], those RNA aptamers have yet to be …

… aptamer was improved by performing a second biased SELEX experiment, where the
randomized starting RNA … This second SELEX experiment produced an aptamer with a K d of 2–5 …

… Here, using experimentally validated in silico techniques, we have designed two RNA
aptamers that bind EpCAM with improved affinity over existing aptamers. We confirm that these …

… laboratory to investigate RNA–RNA complexes formed between RNA aptamers and viral RNA
targets from … Lastly, revert the experiment by immobilizing the RNA aptamer instead of the …