RNA-DNA interactions can serve as a signal that triggers de novo DNA methylation in plants.
As yet, this RNA-directed DNA methylation mechanism merely targets transgenes, but it …

… of DNA methylation to the targeted promoter and silence the gene [163]. This demonstrated
that sRNAs could direct DNA methylation to … with AGO4 and directing DNA methylation to …

… In plants, 24-nt small interfering RNAs (siRNAs) are known to guide DNA … to the siRNAs for
de novo DNA methylation, a pathway named RNA-directed DNA methylation (RdDM) [1, 2, 3, …

… -mediated epigenetic pathway is RNA-directed DNA methylation (RdDM), which is the
subject of this Review. Initially detected in plants that were infected with RNA pathogens 3,4 , …

… RNA triggers for DNA methylation can come from … RNA precursors by RNA-dependent
RNA polymerases. The mechanism by which RNA signals are translated into DNA methylation …

… RNA-directed DNA methylation contributes substantially to epigenetic regulation of …
Methylation is guided to homologous DNA target sequences by 24 nt ‘heterochromatic’ small RNAs …

… by multisubunit RNA polymerase II (Pol II), … RNAs that can also guide initial DNA methylation,
thereby enabling subsequent Pol IV-RDR2 recruitment. In both pathways, the small RNAs …

… of cytosine DNA methylation 1 . Eight years later, small interfering RNAs (siRNAs) were
identified as the causal molecule directing the deposition of DNA methylation and methylation of …

… a RNA rolling circle mechanism without involvement of DNA intermediates, it was evident
that de novo DNA methylation was actually RNA-directed. In the presence of RNA molecules …

… Transcriptional gene silencing via RNA-directed DNA methylation (RdDM) guides the …
DNA and remodel chromatin. The final DNA methylation pattern is determined by either DNA …