… sequence parameters for RNA editing Given that we could achieve precise RNA editing
at a … for programming the system against any RNA target in the transcriptome. Sequence …

… RNA base editors, focusing on the assessment and improvement of their editing precision
and safety, pushing the limit of editing … of each CRISPR tool from DNA editing to RNA editing, …

… RNA manipulation is advantageous over DNA editing as it prevents unwanted pleiotropic
effects, and RNA … the recent advances in CRISPR/Cas13 systems for RNA editing, focusing on …

… RNA-seq reads of RNA base-editing experiments were aligned to the hg38 reference
genome with Hisat2 (v.2.0.4) . RNA editing sites were calculated using REDItools 48 with the …

… RNA editing, revealing that Cas9 can act as an RNA-aptamer-binding protein. We demonstrate
that Cas9-based A-to-I editing … off-target specificity with Cas13 RNA editing versions. This …

… and Cas13 will promote RNA-targeting technology … in RNA-targeting CRISPR-Cas systems
as well as advances in applications of these systems in RNA targeting, tracking and editing. …

… editing efficiency. Finally, we show that an adenine base editor 7 can also induce
transcriptome-wide RNA edits. … improved variants with reduced RNA editing activities, and suggest …

… This study highlighted the latest progress in RNA editing targeted by the CRISPR-Cas13 family,
and … , and proposed a future vision of RNA editing targeted by the CRISPR-Cas13 family. …

… such as RNA splicing. In contrast to CRISPR-based DNA-editing approaches, RNA editing
events … Moreover, some RNA-based therapeutics are already FDA approved and their use in …

… RNA editing, nucleic acid detection, and disease diagnosis; however, a constantly active Cas
… Bacteriophage- or prophage-region-encoded anti-CRISPR (acr) gene molecules provide …