Angiotensinogen (AGT) has been shown to have a role in cardiac hypertrophy, while depletion
of the AGT gene in spontaneously hypertensive rats (SHR) has not been investigated. …

… The purpose of the present study was to investigate the effects on blood pressure and
myocardial hypertrophy in SHRs (spontaneously hypertensive rats) of RNAi (RNA interference) …

[Effects of RNA interference targeting angiotensin-converting enzyme on the blood pressure
and myocardial remodeling in spontaneously hypertensive rats]. - Abstract - Europe PMC …

… hypertension of different genesis. The main goal of this study was to investigate the efficacy
of the RNA interference (RNAi… vasodilator potential in spontaneously hypertensive rats (SHR)…

… Spontaneously hypertensive rats (SHR) are used as a model of human essential hypertension.
It … Persistent hypertension begins when rats reach ≈2 months of age and is followed by a …

… in spontaneously hypertensive rats to test whether angiotensinogen reduction would lower
their hypertensive blood pressures. The ASODN lowers hypertensive blood pressures to …

… cortex of spontaneously hypertensive rats (SHRs) and normotensive Wistar‑Kyoto (WKY)
rats. The ipsilateral renal cortex was obtained from 15‑week‑old SHRs and WKY rats whose …

… spontaneous hypertensive rats (SHRs) in comparison with Wistar rats, finding that micro
RNA-21 (miR-21) was dramatically induced in SHRs relative to Wistar rats. We designed a …

… -Con) were carried out in spontaneously hypertensive rats (SHR) and normotensive Wistar
… is easier to achieve tissue-specific RNA interference because the flexibility of Pol II promoter …

… tensin receptor subtype 1a (AT1aR) by RNA interference. Hypertension. 2005;45:115-9.
23. … nanosphere in spontaneous hypertensive rat. J Korean Soc Hypertens. 2010;16:28-38. …