Nudix‐type RNA pyrophosphohydrolase provides homeostasis of virulence factor pyocyanin and functions as a global regulator in Pseudomonas aeruginosa

M Kujawa, M Lirski, M Ziecina, J Drabinska… - Molecular …, 2017 - Wiley Online Library
… , we present evidence that the PA0336 protein from Pseudomonas aeruginosa is a functional
homologue of the E. coli RppH RNA pyrophosphohydrolase. Phenotypic analysis of a P. …

Effect of the RNA pyrophosphohydrolase RppH on envelope integrity in Escherichia coli

U Choi, YH Park, YR Kim, YJ Seok… - FEMS Microbiology …, 2017 - academic.oup.com
… In this study, we investigated the physiological roles of the RNA pyrophosphohydrolase
RppH by deleting the rppH gene and analyzing various phenotypes. The rppH mutant was …

[HTML][HTML] Searching for Biological Function of the Mysterious PA2504 Protein from Pseudomonas aeruginosa

J Drabinska, K Steczkiewicz, M Kujawa… - International Journal of …, 2021 - mdpi.com
… 5′-triphosphorylated RNA transcripts and via participation in RNA decay regulates expression
of different genes [4]. It was later observed that RppH of P. aeruginosa can functionally …

[HTML][HTML] Identification of the RNA pyrophosphohydrolase RppH of Helicobacter pylori and global analysis of its RNA targets

T Bischler, P Hsieh, M Resch, Q Liu, HS Tan… - Journal of Biological …, 2017 - ASBMB
RNA degradation is crucial for regulating gene expression in … to a monophosphate can
trigger RNA decay by exposing the … ), is an RNA pyrophosphohydrolase that triggers RNA

[HTML][HTML] The Pseudomonas aeruginosa RpoH (σ32) Regulon and Its Role in Essential Cellular Functions, Starvation Survival, and Antibiotic Tolerance

KS Williamson, M Dlakić, T Akiyama… - International Journal of …, 2023 - mdpi.com
… sigma factor, σ 32 (RpoH), which responds to misfolded protein stress and directs the RNA
polymerase to the promoters for genes required for protein refolding or degradation. In P. …

[HTML][HTML] Dinucleoside polyphosphates act as 5′-RNA caps in bacteria

O Hudeček, R Benoni, PE Reyes-Gutierrez… - Nature …, 2020 - nature.com
… coli enzymes RNA 5′-pyrophosphohydrolase (… of RNA in prokaryotes and on the role of
RNA caps. We bring evidence that small molecules, such as Np n Ns are incorporated into RNA

Principles of RNA and nucleotide discrimination by the RNA processing enzyme RppH

A Gao, N Vasilyev, A Kaushik, W Duan… - Nucleic acids …, 2020 - academic.oup.com
… -end-dependent RNA degradation by removing orthophosphate … and (p)ppGpp, which each
resemble the 5′-end of RNA. A … 5′-diphosphorylated nucleotides as with RNA, the enzyme …

[HTML][HTML] The pyrophosphohydrolase RppH is involved in the control of RsmA/CsrA expression in Azotobacter vinelandii and Escherichia coli

LP Bedoya-Pérez, LF Muriel-Millán, S Moreno… - Microbiological …, 2018 - Elsevier
… pathway but has preference for RNA substrates with 5′-… and Pseudomonas aeruginosa,
the pyrophosphohydrolase … The RNA pyrophosphohydrolase RppH, a member of the …

Regulation of RNA processing and degradation in bacteria

A Trinquier, S Durand, F Braun, C Condon - Biochimica et Biophysica Acta …, 2020 - Elsevier
… to a monophosphate by an enzyme called RNA pyrophosphohydrolase (RppH) (see below).
… Dip of Pseudomonas aeruginosa. Indeed, this phage protein interacts with two RNA binding …

The rph-1-Encoded Truncated RNase PH Protein Inhibits RNase P Maturation of Pre-tRNAs with Short Leader Sequences in the Absence of RppH

KE Bowden, NS Wiese, T Perwez… - Journal of …, 2017 - Am Soc Microbiol
P in the absence of RppH, an RNA pyrophosphohydrolase that converts primary 5′
triphosphates into 5′ monophosphates. The data presented indicate that the presence of the …