Comprehensive profiling of circulating microRNA via small RNA sequencing of cDNA libraries reveals biomarker potential and limitations

Z Williams, IZ Ben-Dov, R Elias… - Proceedings of the …, 2013 - National Acad Sciences
… circulating biomarkers (27). To evaluate the potential use of circulating miRNAs as
biomarkers of disease, we characterized miRNAs present in circulation using a deep-sequencing

Comprehensive RNA-sequencing analysis in serum and muscle reveals novel small RNA signatures with biomarker potential for DMD

AML Coenen-Stass, H Sork, S Gatto, C Godfrey… - … Therapy-Nucleic Acids, 2018 - cell.com
… small RNAs (sRNAs), including microRNAs (miRNAs), are promising biomarkers for … levels
on a global scale, we performed sRNA sequencing in four muscle types and serum from wild-…

RNA-seq profiling reveals PBMC RNA as a potential biomarker for hepatocellular carcinoma

Z Han, W Feng, R Hu, Q Ge, W Ma, W Zhang, S Xu… - Scientific reports, 2021 - nature.com
… mononuclear cell (PBMC) RNA using RNA-seq technology and compared the transcriptome
… study, and PBMC RNA was sequenced from all samples. Sequencing data were analyzed …

RNA-Seq profiling of circular RNAs in human colorectal Cancer liver metastasis and the potential biomarkers

H Xu, C Wang, H Song, Y Xu, G Ji - Molecular cancer, 2019 - Springer
… In this study, the secondary sequencing was used to profile … both of them had the potential
for diagnosing liver metastases from … may serve as a potential diagnostic biomarker for liver …

High-throughput RNA sequencing analysis of plasma samples reveals circulating microRNA signatures with biomarker potential in dengue disease progression

J Saini, B Bandyopadhyay, AD Pandey… - Msystems, 2020 - Am Soc Microbiol
RNAs, extremely stable and easily detectable in the plasma; thus, they have potential as
biomarkers for … that have biomarker potential for dengue infection and disease progression. …

Identification of potential blood biomarkers for early diagnosis of Alzheimer's disease through RNA sequencing analysis

D Shigemizu, T Mori, S Akiyama, S Higaki… - Alzheimer's research & …, 2020 - Springer
… tools for detecting those biomarkers, whole RNA sequencing (RNA-seq) of human peripheral
… study identified potential biomarkers for early diagnosis of AD from RNA sequencing data. …

RNA-Seq profiling of serum exosomal circular RNAs reveals Circ-PNN as a potential biomarker for human colorectal cancer

Y Xie, J Li, P Li, N Li, Y Zhang, H Binang, Y Zhao… - Frontiers in …, 2020 - frontiersin.org
… circRNAs as potential biomarkers for … RNA sequencing (RNA-seq) analysis using fifty
CRC and fifty healthy control serum samples to identify CRC-related circRNAs. The sequencing

RNA sequencing reveals LINC00167 as a potential diagnosis biomarker for primary osteoarthritis: A multi-stage study

L Jiang, Y Zhou, J Shen, Y Chen, Z Ma, Y Yu… - Frontiers in …, 2021 - frontiersin.org
potential biomarkers for OA diagnosis. Methods: We first performed an exploration of RNA-sequencing
in … The third stage investigated the potential value of validated lncRNA in the early …

Long non-coding RNAs: mechanisms, experimental, and computational approaches in identification, characterization, and their biomarker potential in cancer

A Chowdhary, V Satagopam, R Schneider - Frontiers in Genetics, 2021 - frontiersin.org
… The top highly connected lncRNAs(top 10) putatively having important regulatory
mechanisms in these modules were selected for having biomarker potential in regards to chronic …

RNA-Seq identifies circulating miR-125a-5p, miR-125b-5p, and miR-143-3p as potential biomarkers for acute ischemic stroke

S Tiedt, M Prestel, R Malik, N Schieferdecker… - Circulation …, 2017 - Am Heart Assoc
… We used RNA sequencing to study expression changes of circulating microRNAs in a
discovery sample of 20 patients with IS and 20 matched healthy control subjects. We further …