… be leveraged for new therapeutic approaches. We also discuss how condensates may aid
… biomolecular condensates and RNA therapeutics to deliver novel opportunities for patients. …

… , such as transcription, RNA processing, and translation (… RNA biology, here we focus on
biomolecular condensates containing RNA and protein, such as “transcriptional condensates…

… and RNA molecules with related functions. New insights from … key features of biomolecular
condensates, note where they … cancer therapeutics can be greatly influenced by condensates, …

… community within condensates provides an untapped source of therapeutic agents. Notably,
… Similarly, helicase action controls the partitioning of RNA within biomolecular condensates …

… The best-studied example of vectoral organization of biochemistry via biomolecular
condensation is the production of ribosomes in the nucleolus, where pre-ribosomal RNA is …

… of biomolecular condensates — transient liquid-like droplets made up of proteins and RNA
— is … “Depending on the specific therapeutic situation and the specific target and the specific …

… the possibility of therapeutic targeting of condensates. This … and biomolecular condensate
models, multiple scenarios of … between condensate components, such as protein, RNA, and …

… nucleic acid-based therapeutics targeting RNA, partition into and modulate certain …
biomolecular condensates to facilitate the development of novel disease mechanistic and …

… as tools for potential drug or gene therapy delivery. The recent advances in generating …
out what makes specific proteins and RNAs partition into condensates in vivo. Since in vivo …

… Further understanding of condensates may provide new therapeutic opportunities for … occur
within condensates that compartmentalize and concentrate the protein and RNA molecules …