In vitro developmental toxicology assays: A review of the state of the science of rodent and zebrafish whole embryo culture and embryonic stem cell assays

K Augustine‐Rauch, CX Zhang… - … Part C: Embryo …, 2010 - Wiley Online Library
… Three rodent-based developmental toxicity assays including the mouse embryonic stem
cell test (EST), the rodent micromass assay (MM), and the rodent whole embryo culture (WEC) …

Xenobiotic kidney organogenesis from human mesenchymal stem cells using a growing rodent embryo

T Yokoo, A Fukui, T Ohashi, Y Miyazaki… - Journal of the …, 2006 - journals.lww.com
… develop the renal unit in the rodent environment without immunosuppressive drugs. Although
… that the rodent embryo may facilitate immunotolerance for both self and xenogenic cells if …

Human embryonic stem cell–derived cardiomyocytes and cardiac repair in rodents

LW van Laake, R Passier, PA Doevendans… - Circulation …, 2008 - Am Heart Assoc
… Only rarely (<1%) were cells positive for the endothelial cell … , whereas staining of the grafts
for stem cell markers (Tra-1-60, … Human embryonic stem cell-derived cardiomyocytes survive …

Human mesenchymal stem cells in rodent whole-embryo culture are reprogrammed to contribute to kidney tissues

T Yokoo, T Ohashi, JS Shen… - Proceedings of the …, 2005 - National Acad Sciences
… adult stem cells by using the kidney as a target organ. Cultivation of human mesenchymal
stem cells in growing rodent embryos … We show that a combination of whole-embryo culture, …

[HTML][HTML] Pluripotency of embryo-derived stem cells from rodents, lagomorphs, and primates: Slippery slope, terrace and cliff

P Savatier, P Osteil, PPL Tam - Stem cell research, 2017 - Elsevier
cells in the embryo, also display limitless self-renewal activity. Self-renewing stem cells that
are derived from the rodent embryosEmbryos of certain murine strains and rodent species …

Capture of authentic embryonic stem cells from rat blastocysts

M Buehr, S Meek, K Blair, J Yang, J Ure, J Silva… - Cell, 2008 - cell.com
Embryonic stem (ES) cells have been available from inbred mice since 1981 but have not
been validated for other rodentsrodents forms a cup-shaped structure termed the egg cylinder. …

Culture of rodent spermatogonial stem cells, male germline stem cells of the postnatal animal

H Kubota, RL Brinster - Methods in cell biology, 2008 - Elsevier
… mouse embryonic fibroblast (MEF) feeders or STO feeder cells have … stem cells, such as
embryonic carcinoma (EC) stem cells, embryonic stem (ES) cells, or embryonic germ (EG) cells (…

Embryonic stem cell transplants as a therapeutic strategy in a rodent model of autism

JJ Donegan, AM Boley, DJ Lodge - Neuropsychopharmacology, 2018 - nature.com
… Here we used a dual-reporter embryonic stem cell line to generate enriched populations of
… I:C rodent model of autism. PV interneuron transplants were able to decrease pyramidal cell

[HTML][HTML] Non-human primate and rodent embryonic stem cells are differentially sensitive to embryotoxic compounds

L Walker, L Baumgartner, KC Keller, J Ast, S Trettner… - Toxicology Reports, 2015 - Elsevier
… -based embryonic stem cell test (… embryonic stem cells (ESCs) of a non-human primate to
skeletal teratogens with mouse ESCs hypothesizing that inclusion of non-human primate cells

Controlling and monitoring stem cell safety in vivo in an experimental rodent model

C Leten, VD Roobrouck, T Struys, TC Burns… - Stem Cells, 2014 - academic.oup.com
… into several cell types of which some can result in unwanted side effects. Well-known
examples of this are embryonic stem cells (ESCs) [4] and induced pluripotent stem cells (iPSCs) …